Researchers at the Scripps Research Institute Florida campus have refined the already state-of-the-art gene-editing system CRISPR. The new improvements boost the ability of CRISPR to target, cut and paste genes in human and animal cells and helps to address the concerns of off target gene mutations raised in a recent study [1]. What is CRISPR? CRISPR…

We are holding our second Journal Club live stream event on June 27th at 13:00 EST/18:00 UK.  Oliver Medvedik, Ph.D. and the Ocean level Patrons will be discussing the research and the implications of epigenetic alterations on aging and as a primary aging process with Dr. Oliver Medvick. The event will be streamed live to our Facebook page…

Whilst looking through recent papers about biomarkers and this recent open access paper crossed my desk. The paper is the latest in a line of top to bottom reviews of aging biomarkers for humans. With companies like Unity Biotechnology and the David Sinclair lab entering human clinical trials later this year for senescent cell removal…

It has been a busy few months since we launched our Lifespan Heroes campaign on Lifespan.io the aim of which is to help us expand the scale and scope of our activities. I thought it was a great time to tell you about the things we have been doing thanks to the support of our…

Earlier this year the second Scripps Florida Symposium was held and now this open access paper reports on the event. The title of of the event was ‘Advances in Therapeutic Approaches to Extend Healthspan’ and was held on January 22nd–25th, 2017 at The Scripps Research Institute in Jupiter, Florida. It is once again very refreshing…

Today we thought it was a good time to take a look at a new study that demonstrates that increasing autophagy is a good approach to slowing aging and could be the foundation for a variety of therapies to treat age-related diseases. What is Autophagy? Autophagy is an intracellular degradation system that delivers unwanted cell…

LEAF/Lifespan.io is teaming up with the Major Mouse Testing Program (MMTP) for a special longevity panel with Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and a number of guests. The MMTP will be streaming the panel live to their Facebook page and we invite you to join us. The panel will also…

Many of you may already know about billionaire entrepreneur Jim Mellon and his interest in rejuvenation biotechnology. But for those of you who do not, we would like to introduce you to him and his exciting work. About Jim Mellon Jim Mellon is an entrepreneur and investor with interests in several sectors. He also holds…

As part of our series covering the various researchers working on aging, we finally caught up with Dr. Michael Lustgarten author of ‘Microbial Burden: A Major Cause Of Aging And Age-Related Disease’ and we did this short interview which we hope may be of interest to you.     Hi Mike can you tell us a…

As human life expectancy has increased throughout the 20th and 21st centuries this has led to a steady increase in the population of older people. With that increase has come the rise of age-related diseases and disabilities. As a result it is becoming ever more important to develop preventative strategies to monitor and maintain health…

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