History Nicotinic acid is a form of water-soluble vitamin B3. Vitamin B3 and was discovered in 1937 by American biochemist Conrad Elvehjem and as a result cured pellagra, a disease caused by niacin deficiency that causes horrible skin lesions, diarrhea, dementia and even death. This compound is now commonly marketed as niacin and is the…

The SENS Research Foundation has announced a collaboration with the Buck institute for Research on Aging. The two foundations have collaborated a great deal in the past and the focus of this new research is to be work on cellular senescence in relation to the age-related decline of the immune system. This research was made possible through…

Science and technology play a vital role for human prosperity! In its ideal form science is a systematic method that builds and organizes knowledge in the form of testable explanations to understand the world in an objective and logical way and through this derive predictions about the future. Therefore science stands in sharp contrast to…

Research is increasingly finding a link between the aging process and the lifelong exposure to pathogens. Researchers in this recent study kept mice in a germ free environment and found that the mice had significantly lower levels of inflammation and a marked improvement in their average lifespan[1]. This correlates with another study where mice were…

Alpha-lipoic acid is a common supplement but what about its geroprotective properties? We take a look at this supplment in another of our geroprotector articles. History Alpha-lipoic acid (ALA) was first discovered in 1937 when Snell discovered that a type of bacteria relied on potato juice to reproduce[1]. This led to alpha-lipoic acid being known…

Parkinson’s disease is one of the most well known of the neurodegenerative diseases. The symptoms include tremors and loss of motor control which are caused by the loss of dopamine producing neurons in the brain. In fact most of us lose these neurons as we age, but to a lesser degree. Parkinson’s sufferers have a…

The biotechnology company PureTech are moving towards human clinical trials with a new therapy that may slow down the aging process and combat age-related disease. The company has licensed two new drug candidates, derivatives of the drug Rapamycin, from pharmaceutical giant Novartis. PureTech have recently announced a joint venture with Novartis called resTORbio and are…

DNA is a critical part of the cell, it is the instruction manual for building cells. Whilst DNA is well protected within the cell nucleus damage does occur, therefore DNA repair is absolutely essential for cell function, cell survival and the prevention of cancer. The good news is cells are able to repair damaged DNA…

Magnesium is a common element and is found in a variety of foods but not everyone gets enough of this essential element which is vital for cellular processes. History of Magnesium It was Joseph Black who recognized magnesium as an element back in 1755. However, it was first isolated by Sir Humphry Davy in 1808 many…

The breaking news today is that yet another research group has entered the field of senescent cell clearance to treat aging. Therapies that remove senescent cells are known as senolytics and they have been a hot topic for the past year or so. Before we talk about the new study let’s take a look at…

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