The CRISPR system (Clustered Regularly Interspersed Palindromic Repeats) has exploded onto the biotech sector as a relatively simple, highly efficient and fast method for precisely introducing breaks into genomic loci [1-2]. The realization that it is a prokaryotic acquired immune system, although less mentioned, has been equally paradigm changing [3]. Ironically, it’s the system’s high…

On May 16-19th renowned researchers and advocates of healthy life extension will gather in Paris to discuss recent breakthroughs in regenerative medicine. The conference organized by the International Cell Senescence Association (ICSA) “The Ins and Outs of Cellular Senescence: Understanding the Biology to Foster Healthy Aging and Suppression of Disease” will take place in the…

Spring is the best time to celebrate life and remember all the good things we have achieved to improve and protect human life. One of the organizations which contributed the most to the development of healthcare systems around the globe is the World Health Organization founded by the United Nations. WHO’s Constitution came into force…

The battle against aging is not going to be an easy one, and it will likely require the most refined tools modern science has to offer. Among them, artificial intelligence may be one of the most promising, and is being extensively used by biogerontology researchers such as Dr. Alex Zhavoronkov. Boasting an impressive collection of…

The new research work on senolyic drugs by Baar et al. uses a rationally designed molecule that selectively targets senescent cells in vivo, both in an accelerated aging mouse model, and in normally aged mice as well, with few if any side effects[1]. Senolytics are a new class of potential anti-aging drugs that function by specifically…

Science and technology play a vital role for human prosperity! In its ideal form science is a systematic method that builds and organizes knowledge in the form of testable explanations to understand the world in an objective and logical way and through this derive predictions about the future. Therefore science stands in sharp contrast to…

Research is increasingly finding a link between the aging process and the lifelong exposure to pathogens. Researchers in this recent study kept mice in a germ free environment and found that the mice had significantly lower levels of inflammation and a marked improvement in their average lifespan[1]. This correlates with another study where mice were…

Alpha-lipoic acid is a common supplement but what about its geroprotective properties? We take a look at this supplment in another of our geroprotector articles. History Alpha-lipoic acid (ALA) was first discovered in 1937 when Snell discovered that a type of bacteria relied on potato juice to reproduce[1]. This led to alpha-lipoic acid being known…

Parkinson’s disease is one of the most well known of the neurodegenerative diseases. The symptoms include tremors and loss of motor control which are caused by the loss of dopamine producing neurons in the brain. In fact most of us lose these neurons as we age, but to a lesser degree. Parkinson’s sufferers have a…

The biotechnology company PureTech are moving towards human clinical trials with a new therapy that may slow down the aging process and combat age-related disease. The company has licensed two new drug candidates, derivatives of the drug Rapamycin, from pharmaceutical giant Novartis. PureTech have recently announced a joint venture with Novartis called resTORbio and are…

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