As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissues of which they are part; instead, they emit a range of potentially harmful chemical signals that encourage nearby cells to enter the same senescent state. Their presence causes many problems: they…

The SENS Research Foundation (SRF) is a 501(c)(3) non-profit organization whose focus is on developing and ensuring widespread access to rejuvenation biotechnologies meant to bring the pathologies of old age under comprehensive medical control. SRF was co-founded in March 2009 by Michael Kope, Dr. Aubrey de Grey, Jeff Hall, Sarah Marr, and Kevin Perrott. The approach to…

Today, February 21, is the birthday of Jeanne Louise Calment – the oldest verified human being ever, who managed to live an amazing 122 years and 164 days! Jeanne was an independent and positive person, and she managed to live all alone until age 110. After a fire in her apartment, she moved into a nursing home,…

Today, we take a look at one of the more unusual supplements that has been used in traditional medicine for many years. History of honokiol Honokiol is a lignan isolated from the bark, seed cones, and leaves of the trees of various Magnolia species. Honokiol, along with other active molecules in magnolia, such as magnolol…

Glucosamine is one of the most commonly used supplements frequently taken to promote joint health and treat other aches, but there really is more to this dietary supplement than first meets the eye. History of glucosamine Glucosamine was originally discovered during the 1960s in Italy, by pharmacologist Professor Luigi Rovati, the founder of pharmaceutical giant…

The development pipeline for new drugs and therapies is a long one, and, on average, it can take up to 17 years to research, test, and bring a new product to market [1]. The reasons for this are myriad and complex, and they include the demanding test phases required for safety and efficacy, preclinical tests,…

Most of the generation born in the 1980s enjoyed watching the science-fiction adventure comedy film “Back to the future”. The plot is built around the idea that, by using a time machine, one can go back in time to fix things that have gone wrong, in order to help the present get back to normal…

The rejuvenation research community is very diverse. Despite each of us having their favorite projects or directions of activity, the achievement of our common goal – the extended period of health and productivity – is highly dependent on this diversity. We need advocacy organizations to educate the public and fundraise actively, in order to support…

Today we will cover a story about how a member of our community, Mike Daniels, car mechanic turned cancer researcher, was inspired by the work of Dr. Aubrey de Grey and the SENS Foundation to address age-related diseases. What follows is an emotional, gritty but honest life story of someone who took action and is now doing amazing…

The world is currently experiencing a period of rapid population aging, with estimates stating that by 2050 about 22% of the global  population will be aged 60 years or older;  by the end of this century, that percentage might be potentially as high as 33%. This trend is so pronounced worldwide and so impactful that…

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