History Niacin is a form of water-soluble vitamin B3. In 1937, this vitamin was discovered in yeast and meat by American biochemist Conrad Elvehjem. It was found to cure pellagra, a disease that is caused by vitamin B3 deficiency and that causes horrible skin lesions, diarrhea, dementia, and even death. This compound is now commonly…

During my recent journey to Saint-Petersburg to attend the in situ education program of the International Institute on Ageing of the United Nations, Malta (INIA), I asked one of the main speakers, former Head of the UN Programs on Ageing Dr. Alexandre Sidorenko, to find a few minutes to talk about his work. After joining…

One of the most frequent questions we get from the general public is “When will rejuvenation therapies arrive?” While young people might be able to wait for a few more decades, middle-aged people are much more concerned. The development of new drugs and therapies takes 17 years on average, but this only begins when the…

Today, we bring you an interview with Dr. Marvin Formosa, director of the International Institute on Ageing of the United Nations, Malta (INIA). First, let’s find out how the issue of population aging was first introduced into the agenda of the United Nations and why the UN body focused on aging is located in Malta….

The SENS Research Foundation has announced a collaboration with the Buck Institute for Research on Aging. The two foundations have collaborated a great deal in the past, and the focus of this new research is to involve cellular senescence in relation to the age-related decline of the immune system. This research was made possible through the generous…

The CRISPR system (Clustered Regularly Interspaced Short Palindromic Repeats) has exploded onto the biotech sector as a relatively simple, highly efficient, and fast method for precisely introducing breaks into genomic loci [1-2]. The realization that it is a prokaryotic acquired immune system, although less often mentioned, has been equally paradigm changing [3]. Ironically, it’s the…

On May 16-19th, renowned researchers and advocates of healthy life extension will gather in Paris to discuss recent breakthroughs in regenerative medicine. The conference organized by the International Cell Senescence Association (ICSA), “The Ins and Outs of Cellular Senescence: Understanding the Biology to Foster Healthy Aging and Suppression of Disease”, will take place in the…

Spring is the best time to celebrate life and remember all the good things that we have achieved to improve and protect human life. One of the organizations which contributed the most to the development of healthcare systems around the globe is the World Health Organization founded by the United Nations. WHO’s constitution came into…

The battle against aging is not going to be an easy one, and it will likely require the most refined tools modern science has to offer. Among them, artificial intelligence may be one of the most promising and is being extensively used by biogerontology researchers such as Dr. Alex Zhavoronkov. Helping to drive progress in…

The new research work on senolyic drugs by Baar et al. uses a rationally designed molecule that selectively targets senescent cells in vivo, both in an accelerated aging mouse model, and in normally aged mice as well, with few if any side effects[1]. Senolytics are a new class of potential anti-aging drugs that function by specifically…

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