As we reported in an article yesterday, researchers are becoming increasingly interested in the potential of changing the ratio of types of macrophages present in the body to facilitate tissue regeneration and healing. This is a line of research that covers a number of topics, including aging, regeneration, tissue repair, and inflammation. Over the last…

Today we will be looking at a new study that is attempting to treat atherosclerosis, one of the biggest age-related killers globally. As we age, our risk of developing atherosclerosis rises along with related conditions, such as hypertension. We will be taking a look at new research that has reversed atherosclerosis in mice and is…

CRISPR (otherwise known as “Clustered Regularly Interspaced Short Palindromic Repeat”) is a gene editing system, but it is not a human invention. It was originally part of the antiviral ‘immune system’ of a particular form of bacteria. Unlike our immune system, which destroys cells infected with viruses, CRISPR seeks to destroy the actual virus itself,…

A few days ago, at the international exhibition Geek Picnic 2017 in Moscow, LEAF director Elena Milova had the opportunity to talk with the founder of Sci-Hub, Alexandra Elbakyan. The Sci-Hub website is devoted to providing scientists, students, and researchers with free access to scientific publications which would otherwise be locked behind paywalls. In this…

LEAF Director Elena Milova recently attended the International Longevity and Cryopreservation Summit in Madrid and gave a talk about effective advocacy and how we can engage better with the public as advocates for rejuvenation biotechnology. Her talk touches upon effective message delivery as well as the basic principles of teaching, known as the didactic principles….

Researchers at the Scripps Research Institute Florida campus have refined the already state-of-the-art gene-editing system CRISPR. The new improvements boost the ability of CRISPR to target, cut, and paste genes in human and animal cells and helps to address the concerns of off-target gene mutations raised in a recent study[1]. What is CRISPR? CRISPR is short…

LEAF director Elena Milova was recently at the International Longevity and Cryopreservation Summit in Madrid. During the conference, she caught up with life extension advocate Didier Coeurnelle. In this interview, Didier discusses his projects and shares advice to the community regarding what kind of activities can help foster progress in the development of rejuvenation biotechnology. …

On the 9th of June, we teamed up with the Major Mouse Testing Program (MMTP) for a live stream longevity panel on the MMTP Facebook page. The panel included Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik, MMTP coordinators Steve Hill and Elena Milova, Lifespan.io President Keith Comito, and one of the most…

We are holding our second Journal Club live stream event on June 27th at 13:00 EST/18:00 UK. Oliver Medvedik, Ph.D., and the Ocean level Patrons will be discussing the research and the implications of epigenetic alterations on aging and as a primary aging process. The event will be streamed live to our Facebook page for viewers to…

Whilst looking through recent papers about biomarkers, this recent open access paper crossed my desk. The paper is the latest in a line of top-to-bottom reviews of aging biomarkers for humans. With companies like Unity Biotechnology and the David Sinclair lab entering human clinical trials later this year for senescent cell removal and DNA repair…

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