A new study published by scientists at the Salk Institute recently shows how that changes in the nucleolus of progeria cells and normally aged cells share some characteristics that may allow them to be used as a biomarker for biological age[1]. What is Progeria? Hutchinson-Gilford progeria is a rare genetic disease that causes people to…

The August Journal Club is now available to view. We were joined by Ocean level Lifespan Hero Joel Peterson. We have been talking about a number of new studies in past Journal Clubs, so we thought it was time to take a look at the actual delivery methods and the hurdles we face in the…

If there was a poster child of aging diseases, it would be Alzheimer’s disease. The brains of people suffering from Alzheimer’s disease have deposits of amyloids resulting from the loss of proteostasis. Alzheimer’s disease is accompanied by the presence of amyloid beta protein and tau protein as well as large numbers of activated pro-inflammatory immune…

NEW YORK, NY, August 29, 2017. Lifespan.io is launching a crowdfunding campaign to support MouseAGE, an application to assess visual biomarkers of aging in laboratory animals. This Artificial Intelligence-powered research tool, which is being developed by Youth Laboratories, will help scientists accurately determine the biological age of mice during experiments using advanced visual recognition and…

The old saying “use it or lose it” very much applies to reducing the impact that aging has on the mind and body. Of all the things we can do right now to help stay healthy as we grow older, exercise is probably the most useful. Supplements have questionable results in humans, and none can…

The following is an update from MitoSENS scientist Dr. Matthew “Oki” O’Connor: Hi, everyone! Long time, no update – my fault! As you all saw, our manuscript that was supported by Lifespan.io donors was published last fall. Dr. Boominathan and I have been presenting our results at conferences around the world, and I can tell…

Researchers at the Mayo Clinic have revealed a causal link between senescent cells and bone loss in mice. Senescent cells are one of the hallmarks of aging, and removing them has been proposed as a way to prevent or delay age-related diseases. As your body ages, increasing amounts of your cells become senescent. Senescent cells…

Our crowdfunding platform Lifespan.io, supporting studies on aging and longevity, was founded in August 2015, and this week we are celebrating our second birthday!   We thought that this was a great moment to have a look at what we have achieved with your support: $200k+ raised and 4 research projects successfully funded (and the…

Autophagy means “eating of self” (from Ancient Greek “autó”= self;  and “phagein” = to devour)[1]. Although its name might sound harmful, autophagy appears to have longevity-promoting effects[2]. Here we will explain what autophagy is, how it works, its benefits, and how it plays a role in aging. What is Autophagy? Autophagy is the way cells…

The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by a system that is always present across the body, while the adaptive immune response appears only in response to an infection and is always specific…

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