There is one common public reaction to my talks that bothers me quite a bit. I am worried that after each of my lectures, people will just start taking lots of anti-aging pills without regard for dosage or effectiveness, potentially hurting themselves in the process. This is because one of the most common reactions to…

Idiopathic pulmonary fibrosis is a disease associated with critically short telomeres, and it currently lacks a reliable and effective treatment. Researchers at the Telomere and Telomerase Group at the Spanish National Cancer Research Centre (CNIO) have cured the disease in mice using telomerase therapy to lengthen short telomeres. A proof of concept for an effective…

Thirty-seven-year-old Nick Asoian of Denver unsuccessfully fought Hodgkin’s Lymphoma using conventional cancer treatments for two years.  In 2008, while in New Zealand for a ski race, Nick was diagnosed with the condition. Two bone marrow transplants and two years of chemotherapy combined with radiation therapy didn’t bring his cancer to heel. Nick Asoian. Image source:…

We have talked about the polarization of macrophages in a number of previous articles, but, in short, macrophages can have multiple behavioral profiles that determine what roles they play; this is known as polarization. A new study has identified a regulatory protein that controls this process. Macrophage Polarization For the purposes of this article, we…

As you might recall, in my review of Ending Aging, I said that the book could have benefited from a more in-depth discussion of the benefits of rejuvenation as well as the concerns and objections often raised against it. Anyone else sharing the same feeling will find what they’re looking for in The Abolition of…

Completely bald and with wrinkly skin, the naked mole rat is one of the ugliest creatures around but lives an exceptionally long life for a small mammal. It rarely develops the chronic diseases of aging, such as cancer, and lives 10 times longer than regular rats. The First Non-Aging Mammal In the first significant announcement…

As we age, our bodily functions begin to deteriorate. To some extent, our bodies can cope with these unwelcome changes, but after age 35, some of them become visible. For us living in a world where youth and physical attractiveness are considered an advantage, this gradual loss of young looks can be painful – or…

Stem cell therapies have been developing and evolving rapidly over the last decade, and extracellular vesicles (EVs) are another innovative approach that researchers are exploring. EVs are being explored for their potential as the basis of new cell therapies, taking the signals generated from various types of stem cells and delivering just those signals, rather…

Anastasia Georgievskaya, Alex Zhavoronkov, the MouseAge team, and guests will be taking part in this special panel focusing on AI in aging research hosted by Dr. Oliver Medvedik. The panel will be streamed live on our Facebook page on February 21st at 13:00 EST/18:00 UK. This panel is the result of the MouseAge crowdfunding campaign…

History of Metformin Metformin was originally discovered in 1922, but it did not receive approval for another fifty years or more[1]. The French physician Jean Sterne initiated the first study in humans in the 1950s; it was registered as a medicine in France in 1957, but it was not approved until 1995 in the United…

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