When we first began our work, we wanted to make a real impact and get involved in ushering in a new age of medical technology and progress. To that end, we have continued to grow as an organization every year, with the range of activities we do increasing along with our reach and influence. We have done a lot of things in the last few years since we first created our non-profit organization, and we would like to share some of those achievements with you here.


Since we launched our research fundraising project Lifespan.io in 2015, we have raised over $310,000 for breakthrough research and hosted the following successful crowdfunding campaigns:


MouseAge – Aging Biomarkers


AgeMeter – Aging Biomarkers


CellAge – Synthetic Biology and Biomarkers

OncoSENS – Therapy for ALT Cancer

MMTP: Phase 1 - Senolytics

MMTP – Combination Senolytic Therapies

MitoSENS - Mitochondrial repair

MitoSENS – Mitochondrial Repair


NAD+ Mouse Project – NMN Lifespan Study


We work to make high-impact collaborations with large-scale content creators on platforms like YouTube in order to inform and engage an ever-widening segment of the population on the topic of longevity research. We welcome the opportunity to work on more such initiatives; feel free to contact us if you are a content creator looking to produce well-informed videos on the subject of aging and life extension.


Why Age? Should We End Aging Forever? – Kurzgesagt


How to Cure Aging – During Your Lifetime? – Kurzgesagt


This Is How You Could Live An Extra 100 Years – Life Noggin


LEAF is a 501(c)(3) non-profit organization dedicated to supporting research to end age-related diseases through a program of advocacy, education, and crowdfunding. We have been a top rated non-profit for two years running at Greatnonprofits thanks to the support of our community.


In July 2018, we hosted the Ending Age-related diseases 2018 conference at the Cooper Union in the heart of New York City. The conference saw various industry experts and thought leaders come together for an action-packed day of research and biotech business talks and panels. Due to the success of the conference, we are planning to host a conference in New York every year from now on.


Keith Comito at Ending Age-Related Diseases 2018 — One Second, One Life | LEAF.


Dr. Aubrey de Grey at Ending Age-Related Diseases 2018 — Rejuvenation is Finally an Industry | LEAF.


The Current State of Aging Research — Ending Age-Related Diseases 2018 Panel | LEAF.


Translating Aging Research — Ending Age-Related Diseases 2018 Panel | LEAF.


Since January 2017, we have been reporting on the latest news and happenings in the aging research field. We interview the leading figures in rejuvenation biotech and aging research, report on the latest developments in the industry, create advocacy articles exploring the ethics and social issues of longer lives, and produce educational articles about the biology of aging.

Even More News

More Journal Club



Brought to you by Nicola Bagalà, the Rejuvenation Roundup is our monthly digest, which takes a look at the big news stories involving the industry and helps keep you informed of current developments in the aging research field. To accompany the monthly Rejuvenation Roundup, as of July, we also began to include a podcast version that takes a deeper look at some of the key stories from that particular month and is hosted by Ryan O’Shea of the Future Grind podcast. You can listen to the latest episode below; for more, check out our Rejuvenation Roundup page.


We actively support and drive positive policy change in healthcare and the regulatory system. We work with other groups to engage with the FDA, support freedom of scientific knowledge, take part in community efforts to change policy, and interview lobbyists engaged with high level organizations such as the WHO.

New FDA Regenerative Medicine Framework is Win-Win for Gene Therapies.

Paywall: The Business of Scholarship Documentary in English and Russian.

World Health Organization Puts the Elderly Back in the Picture.

Daria Khaltourina – A Step Closer to Aging Being Classified as a Disease.


In early 2018 we created the Longevity Investors Network (LIN), a project designed to create a network of investors interested in aging research as well as identifying promising startups working in the rejuvenation biotechnology space. The LIN meets every month and new companies working on therapies targeting the aging processes get to pitch to the network of investors, this brings researchers and investors together to help drive progress and funding.


In 2018 we launched the Rejuvenation Roadmap, a curated database tracking the various therapies targeting the aging processes in order to delay, prevent, or even reverse age-related diseases. The roadmap breaks down aging into nine categories of damage, known as the hallmarks, and shows which projects are targeting which hallmarks as well as how far along the clinical trial process they are. This is your one stop shop to see how things are progressing and how far we might be from these technologies being available.


If you would like to get involved directly with our work, support research projects, or help our org continue to grow by becoming a monthly Patron, you can find out how below.

By supporting us with monthly donations, you become a Lifespan Hero, powering the development of Lifespan.io and improving our ability to advance longevity-focused biomedical research. Heroes will be honored on our wall of fame, and we will also be able to offer exciting features to our entire community as key thresholds are reached.
You can donate to us with PayPal via PayPal.me or our official charity page. If you would like a tax receipt for your donation, please email your name and the amount of your donation to [email protected]

Donate now

Donor-Advised Fund
If you work with a donor-advised fund, you can recommend a contribution to LEAF via DAFDirect
You can donate to us via Bitcoin, Bitcoin Cash, Ethereum, or Litecoin by going here: Donate with BTC, ETH, BCH, or LTC. If you would like a tax receipt for your donation, please email your name and the amount of your donation to [email protected]
You can donate via mail by sending your check to: Life Extension Advocacy Foundation 3805 Estella St., Seaford, NY 11783, USA.
Active people willing to lend a hand are most welcome in our fight to end age-related disease. Please fill out our volunteer form if you'd like to be involved directly. You don't need to be a scientist to foster progress, and, in particular, we would love to hear from specialists in the following areas:


• IT and Web Development: PHP, SQL, etc.

•Writers - If you have experience writing articles you can pitch to us here.

•Social media managers


•Graphic artists

•Policy and regulatory experts

Even if you can't help us directly yourself, you may know a friend or organization who can. The diseases of aging affect every person on earth, so we're certainly happy to make friends - please feel free to share any of the contents on this site, our educational materials, or the invite link to our newsletter.
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This is a great way to support us without any extra cost to you, so please set us as your AmazonSmile charity and support our work.
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Thank You!