No more eraserhead: Will blocking epigenetic erasers prevent Alzheimer’s disease?

Just like a well-folded sheet of paper, a tightly coiled segment of DNA doesn’t have much chance of being read. Our cells use this to their advantage, unspooling the genes they need at the moment with negatively charged acetyl groups, and using ‘eraser’ enzymes that remove these groups to roll up the instructions they don’t…

When cancer was just a twinkle in your epigenome’s eye

A friendly genie appears in a puff of smoke and tells you that you’ll develop cancer 20 years hence. However, he offers to send you back in time to any point you wish, so that you can alter events in your life to prevent your cancer. Quickly now, he doesn’t have all day–when do you…

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