Research roundup: The microbiome in neurodegenerative disease, and more

It’s looking increasingly likely that our little bacterial buddies have a major influence on neurodegenerative disease, from producing extra amyloid, to regulating inflammation, to generating free radicals. In mouse models of Alzheimer’s disease, a protein complex that forms part of the nervous system’s innate immune system binds to toxic amyloid-beta, promoting the formation of plaques.

Better together? Testing the first combination therapies for longevity

The normal mode of drug discovery is a pretty singular affair: one compound, one disease. This is enough for many traditional diseases, but when you’re facing a complex phenomenon built on innumerable pathways like aging, where existing treatments only scratch the surface, you need to get a little more creative. complex phenomenon built on innumerable…

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