Cancer’s little helper

A menacing shadow looms large over the body. Lessons we’ve learned from the eternal struggle of organism against cell are etched into the farthest corners of the genome, patches on top of patches, shoring up our weaknesses for the next time the conflict erupts. And yet, even with a standing army dedicated to repairing DNA,…

Are cancer prevention and cellular reprogramming really enemies?

Imagine a physiological love triangle: in one corner, a force with the weight of millions of years of evolutionary programming trained on preventing runaway replication; in the other, the set of epigenetic regulators that must maintain the ability of stem cells to churn out whatever kind of cell they need to. At first glance, the…

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