How many mutations before stem cells go kaput?

Imagine that today is your first day at a brand new job, and your new boss slaps an enormous booklet on your desk, then walks off without a word. The front of the booklet reads “HOW TO DO YOUR JOB”, and underneath in smaller print is the word accountant, and underneath that is the number…

Space aging

People have been talking about terraforming and colonizing Mars since the beginning of space travel, and in the past few years that ambition seems to have gone mainstream. But if we want to conquer the “final frontier” of space, we must first confront that other final frontier. Because, as it turns out, the problem with…

What’s new in media and industry: Who’s who in longevity, and more

Here’s our handpicked selection of the best interviews, blog posts, popular articles, and breaking biotech news of the last two weeks: Want a systematic overview of every organization chipping away at human aging right now? Then you’ll love this nearly 800-page report from the Biogerontology Research Foundation. Put it in your queue for bedtime reading….

Research roundup: The naked (mole rat) truth, and more

What good is a longer life if you have to spend half of it keeping up with the news? Ditch those endlessly scrolling feeds, and instead join us every other week for a concentrated dose of the most exciting developments in the field of geroscience. Here’s the recap: Naked mole rats really do age better,…

James Peyer: Where are stem cell therapies headed?

Someday soon we may be able to replace tissues or entire organs with those grown from a patients’ own stem cells… but just how soon? What challenges do stem cell therapies face on the path of development, as they progress from the lab to the commercial world? James Peyer, investor and former stem cell biologist, answers below…

Research roundup: Muscles from the lab, and more

We know you want to keep up with the relentless march of progress, but sometimes it’s just too relentless. So why not forget all those endlessly scrolling feeds, and instead join us for a bi-weekly concentrated dose of all the most exciting developments in the field of geroscience? Here’s what’s happened in the last two weeks:…

What’s new in media and industry: Laura Deming’s intro to longevity, and more

Just getting started around here, or want to introduce someone new to the world of longevity science? This handy primer from Laura Deming (of Longevity Fund) might be just what the doctor ordered. primerLongevity Fund Ring in the new year with retrospectives of 2017 from Fight Aging! and the Life Extension Advocacy Foundation, then start…

Are cancer prevention and cellular reprogramming really enemies?

Imagine a physiological love triangle: in one corner, a force with the weight of millions of years of evolutionary programming trained on preventing runaway replication; in the other, the set of epigenetic regulators that must maintain the ability of stem cells to churn out whatever kind of cell they need to. At first glance, the…

Video interview with James Peyer: Longevity science from bench to clinic, and everything in between

No one should have to read during the holidays. That’s why we made you a video! I spoke to our own James Peyer about how he got started in the longevity world, the unique challenges of bringing new anti-aging therapeutics to the public, and how his role as an investor allows him to help projects

Research roundup: The importance of energy in Alzheimer’s, and more

Since the world of Alzheimer’s therapeutics hasn’t seen much practical benefit from targeting harmful proteins like amyloid-beta, maybe other approaches like targeting dysfunctional mitochondria are worth exploring in more depth. Apparently, improving mitochondrial function can decrease plaque burden and improve cognition in a mouse model. Why do cancer survivors have shorter lifespans than the rest

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