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At least one group is running trials of stem cell transplants as a potential treatment for age-related frailty syndrome: the scope of the possible in the near term is to find way to incrementally improve the condition, not produce a sizable reversal, but that is an improvement over the current situation, given that there is…

Near the entire corpus of present day medicine for age-related disease, even the comparatively successful treatments, is essentially compensatory in nature. It fails to address in any meaningful way the underlying causes of aging and disease. “Comparatively successful” is presently measured against doing nothing, rather than against the goal of a cure, of controlling the…

Models and trends established across collections of species are used as a tool to try to understand the complex relationship between metabolism and aging, meaning how exactly the natural variations between individuals and species arise from the behavior of cells and interaction with the surrounding environment. This is something of a sideshow to the main…

(Chempetitive Group) During the conference, researchers will discuss how Droplet Digital PCR helps them screen stem cells for harmful mutations as well as how Droplet Digital PCR provides early detection of transplant rejection and delivers absolute quantification of gene expression to investigate cancer.

(Cleveland Clinic) A new Cleveland Clinic study underscores the importance of early detection and treatment of melanoma, the deadliest form of skin cancer. The research, published online today in the Journal of the American Academy of Dermatology, indicates that the sooner patients were treated, the better their survival, particularly for stage I melanoma.

(Jackson Laboratory) The Jackson Laboratory (JAX), a nonprofit biomedical research institution, and Seven Bridges, the leading biomedical data analysis company, today announced a new collaboration to build an NCI-funded data platform to accelerate translational research using patient-derived tumor xenograft (PDX) datasets.

(University at Buffalo) Scientists from For-Robin Inc., a University at Buffalo biotechnology spinoff, have published new scientific results showing that the company’s cancer-fighting antibody can target, penetrate and kill human tumor cells effectively. The findings bring the company closer to human clinical trials.

(American Chemical Society) Breast cancer is the second most commonly diagnosed cancer in women. Fortunately, the rate at which we’re learning about this disease means patients have a lot more treatment options and far better chances of survival than they did 100 years ago. In observance of Breast Cancer Awareness Month, Reactions describes what’s changed…

(Bar-Ilan University) Prof. Uri Nir, of the Mina and Everard Goodman Faculty of Life Sciences at Bar-Ilan University, and his team have identified an enzyme that supports the survival and dissemination of metastatic cells, and developed a synthetic compound that targets the enzyme and kills the metastatic cells in mice with cancer. Their research has…

(The Francis Crick Institute) Researchers at the Francis Crick Institute have discovered a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies.

(University of Bonn) Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural ‘brakes’ in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes. The study, which involved colleagues…

(Elsevier) Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer and the most frequently diagnosed non-Hodgkin lymphoma worldwide (nearly 40 percent of cases). Recent advancements indicate that both the prognosis and choice of treatment of DLBCL may depend on identifying its molecular subtype. In a report in The Journal of Molecular Diagnostics, researchers describe their…

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