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In the research here, injections of blood plasma from young rats are shown to improve autophagy and liver function in old rats. This is interesting given the so far mixed evidence for young to old plasma transfer to be beneficial. There is, however, a history of research to show that increased levels of the cellular…

Is random mutational damage to nuclear DNA a sizable cause of aging? The consensus in the scientific community on that question is that it is an important cause, with the theory being that this results in sufficient change in protein production and cellular behavior to produce degraded function. That consensus is challenged, however, and at…

WASHINGTON — Consuming soy foods (such as soy milk, tofu and edamame) and cruciferous vegetables (such as cabbages, kale, collard greens, bok choy, Brussels sprouts, and broccoli) may be associated with a reduction in common side effects of breast cancer treatment in breast cancer survivors, say a team of scientists led by Georgetown Lombardi Comprehensive…

PITTSBURGH, Dec. 11, 2017 – Young adults who use electronic cigarettes are more than four times as likely to begin smoking tobacco cigarettes within 18 months as their peers who do not vape, according to new University of Pittsburgh research. The findings demonstrate that e-cigarettes are serving as a gateway to traditional smoking, contrary to…

IMAGE: Andrew Hung, M.D., with the “black box ” recorder and da Vinci Surgical System. view more  Credit: Ricardo Carrasco III LOS ANGELES – You may know that your surgeon is using the latest minimally invasive technology for your surgery, but how do you know if they’ve mastered it? To help answer that question, researchers at…

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn’t work when it comes to…

ATLANTA – Daily low doses of the immune signaling protein interleukin-2 (IL-2) can safely benefit patients who develop chronic graft-versus-host disease following stem cell transplants, including particular benefit in pediatric patients in one small study, report scientists from Dana-Farber Cancer Institute. Dana-Farber researchers, who have pioneered the use of IL-2 in post-transplant patients, presented four…

ATLANTA – Although people with multiple myeloma usually respond well to treatment, the blood cancer generally keeps coming back. Following genetic changes in how the disease evolves over time will help to understand the disease and, eventually, deliver more effective treatments. Researchers now have successfully demonstrated techniques to track these alterations over time by analyzing…

ATLANTA – In a Phase 1 trial, patients with an advanced or aggressive form of systemic mastocytosis (AdvSM), a rare blood disorder, had rapid and durable responses with few adverse effects following treatment with an investigational drug that targets the genetic mutation found in more than 90 percent of cases. The once-daily pill, BLU-285, targets…

ATLANTA — Researchers at Dana-Farber Cancer Institute have carried out the largest genomic analysis of patients with smoldering multiple myeloma (SMM), a precursor to full-blown blood cancer that doesn’t show outward symptoms. The next-generation sequencing project “will help to explain the biology of the disease and how it unfolds through time from asymptomatic stages to…

IMAGE: This is Sattva Neelapu, M.D. view more  view more  Credit: MD Anderson Cancer Center A study involving the recently approved CD19-targeting chimeric antigen receptor (CAR) T cell therapy shows that 42 percent of patients with aggressive large B-cell lymphoma remained in remission at 15 months following treatment with axi-cel (marketed as Yescarta™). The study, named…

IMAGE: This is how CAR-T cell therapy harnesses a patient’s immune system to fight cancer. view more  Credit: Loyola Medicine MAYWOOD, IL – Loyola University Medical Center is the only Chicago center that participated in the pivotal clinical trial of a groundbreaking cancer treatment that genetically engineers a patient’s immune system to attack cancer cells. Patrick…

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