$26.5 million grant to fund first large-scale study of African-American men with prostate cancer

Johns Hopkins Kimmel Cancer Center will participate in a $26.5 million effort to conduct the first large-scale, multi-institutional study on African-American men with prostate cancer to better understand why they are at higher risk for developing more aggressive forms of the disease and why they are more likely to die from it.

The RESPOND study, funded by grants from the National Cancer Institute, the National Institute on Minority Health and Health Disparities and the Prostate Cancer Foundation, and led by the Keck School of Medicine of University of Southern California, will look at the role of social stressors and genetics in the development of prostate cancer in African-American men. Researchers hope to recruit 10,000 African-American men nationwide to participate in the study.

“African-American men have been disproportionately affected by prostate cancer, and this study brings together researchers from across the country to figure out why, enabling the threat of prostate cancer to be reduced for all men,” said William Nelson, M.D., Ph.D., director of Johns Hopkins Sidney Kimmel Cancer Center.

RESPOND will focus on both biological and social factors that may influence the development of prostate cancer in this group. Social stressors such as discrimination, socioeconomic status, education, early


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