Alexandria, Va., USA – At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Benjamin Chaffee, University of California, San Francisco, USA gave a poster presentation “Nicotine and Carcinogen Exposure by Tobacco Product Type and Dual-Use.” The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.
Tobacco use remains a leading cause of oral cancer but the tobacco landscape is evolving with increasing use of non-cigarette tobacco products and dual-use of multiple product types. Chaffee and co-author Neal Benowitz, also from the University of California, San Francisco, evaluated exposure to known carcinogens according to recent use of different tobacco product types, alone or in combination.
Data was analyzed from the Population Assessment of Tobacco and Health which includes a sample of U.S. adults who provided urine specimens for analysis of tobacco-specific nitrosamines (TSNAs) N’-nitrosonornicotine (NNN), a known oral and esophageal carcinogen, 4-(methynitrosamino)-1-(3)-pyridyle-1-butanol (NNAL), a metabolite of lung carcinogen (NNK) and total nicotine equivalents.
Participants were categorized according to use of combustible — which includes cigarettes, cigars, water pipe, pipes, blunts (marijuana-containing cigars), smokeless — which
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