Wilmington, Del, April 18, 2019 – Scientists at Christiana Care Health System’s Gene Editing Institute and NovellusDx, an Israeli biotechnology company, have deployed a breakthrough CRISPR gene-editing tool to successfully engineer multiple edits simultaneously to fragments of DNA extracted from a human cell, according to a new study published today in The CRISPR Journal. The tool can rapidly reproduce, in a human DNA sample, the unique and complex genetic features of an individual patient’s cancer tumor.
The findings are the result of a collaboration between the Gene Editing Institute and NovellusDx, supported by the U.S.-Israeli Binational Industrial Research and Development (BIRD) Foundation, to develop new approaches to personalized cancer care. NovellusDx plans to integrate these CRISPR-edited DNA samples into its proprietary cancer diagnostic technology as part of a diagnostic test that aims to improve treatment decisions. The company believes DNA samples that have been edited to present the precise genetic make-up of a patient’s cancer tumor can be used to rapidly screen multiple cancer drugs-and identify the course of treatment likely to produce the best outcome for the patient.
“We believe the breakthrough achieved in our in-vitro CRISPR-based parallel mutagenesis technology can significantly improve our
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