About Nicola Bagalà

Nicola is a bit of a jack of all trades—a holder of an M.Sc. in mathematics; an amateur programmer; a hobbyist at novel writing, piano and art; and, of course, a passionate life extensionist. After his interest in the science of undoing aging arose in 2011, he gradually shifted from quiet supporter to active advocate in 2015, first launching his advocacy blog Rejuvenaction before eventually joining LEAF. These years in the field sparked an interest in molecular biology, which he actively studies. Other subjects he loves to discuss to no end are cosmology, artificial intelligence, and many others—far too many for a currently normal lifespan, which is one of the reasons he’s into life extension.
Posts from the author

A few days ago, I wrote an article while on a plane. I’m an expat, and I was flying back to my home country. I’m now in my hometown, where I lived until I was 18. I come back here only seldom, and the last time I visited was four years ago. For the vast…

Yet another important investment in the field of regenerative medicine against aging demonstrates the increasing interest of investors in this industry; on August 2, BioTime, Inc. announced that Juvenescence Limited will buy 14.4 million of its subsidiary AgeX Therapeutics‘ shares for a total of $43.2 million—50% to be paid in cash and 50% with a…

Recently, we’ve published an article explaining why life extension is not a selfish endeavor. As a matter of fact, life extension is a rather altruistic endeavor, though this depends on your interpretation of the definition. Let’s dig deeper. What is altruism? According to the Oxford English Dictionary, altruism is disinterested and selfless concern for the…

This is a fictional story about a man realizing for the first time, under rather unusual circumstances, that he has a deep desire not to age and die. It’s been a few months already, yet that day still feels like yesterday. I am still not convinced that I didn’t lose my mind that day, and…

Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects…

Right now, as I write this article, I’m sitting in a machine that, about 120 years ago, was laughed at as a pipe dream. The machine is a plane, by the way. The onboard wi-fi leaves much to be desired, but if you had told people living in the early 1900s that you could type…

Ichor Therapeutics, a life science company in Lafayette, New York, is one of the big players in the world of rejuvenation biotechnologies. Since its founding in 2013, it has been growing and expanding its portfolio of companies working on therapies against the diseases of aging; on August 1, 2018, Ichor announced the formation of its…

Researchers from the Walter and Eliza Hall Institute, the Monash Institute of Pharmaceutical Sciences, and Cancer Therapeutics CRC have developed a new type of drug that harnesses cellular senescence as a weapon against cancer [1]. Study abstract Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function. Among the genes coding…

At times, meeting people feels like going to the theater. Conversations tend to revolve around the same topics and can sound so cliché that they seem scripted. Of course, it depends on the people—close friends tend to be far more genuine than that—but if you pay attention during a conversation, a certain topic will pop…

Scientists at the Johns Hopkins University reversed hair whitening and loss associated with a high-fat, high-cholesterol diet by using an experimental compound in a mouse model [1]. The compound The experimental compound used by the researchers, called D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D–PDMP) acts by blocking the production of glucosphingolipids (GSL), which are lipids that are abundant in the…

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