A recent study by Harvard Medical School scientists suggests that defective one-carbon metabolism and cellular respiration might contribute to age-related immunosenescence, the decline of immune function typically observed during aging [1]. Abstract T cell-mediated immune responses are compromised in aged individuals, leading to increased morbidity and reduced response to vaccination. While cellular metabolism tightly regulates…

Researchers have discovered a link between the cellular recycling system known as autophagy and the behavior of microglial immune cells during aging. We have discussed the polarization of macrophages in a number of previous articles, and it has become quite a hot topic among researchers in the last few years. Microglia are tissue-resident macrophages in…

Cytomegalovirus (CMV) is a β-herpesvirus that infects the majority of people in the world. It lies dormant in the body, waiting for an opportunity to strike when the immune system is weakened. This persistent virus infects people for their entire lives, and now researchers have discovered how the virus spreads, opening the door to ways…

In November, Dr. Aubrey de Grey, a graduate of the University of Cambridge, was in Spain to attend the Longevity World Forum in the city of Valencia, and he gave a press conference organized by his friend, MIT engineer José Luis Cordeiro. Dr. Aubrey de Grey is the scientific director (CSO) and founder of the…

Today, we present an interview with Reason, the editor of Fight Aging! and co-founder of Repair Biotechnologies. We asked him about the state of rejuvenative therapies, some of which may be available in the near future. Fight Aging! was the first blog that tackled the science of aging in a serious fashion. Many people still…

A study by scientists at the Research Institute of the McGill University Health Centre unveiled a mechanism through which deadly glioblastomas can metastasize. The research has been published in Molecular & Cellular Proteomics [1]. Abstract Glioblastoma multiforme (GBM) is a highly aggressive and heterogeneous form of primary brain tumors, driven by a complex repertoire of…

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