Back in November 2017, the FDA announced a comprehensive policy framework for the development and oversight of regenerative medicine products, including novel cellular therapies. Both draft guidance documents had 90-day comment periods, and we at LEAF joined forces with the Niskanen Center to submit comments to the FDA to ensure that the voice of the…

We are pleased to announce that the Agemeter bags and T-shirts are about to ship to those who backed the project at a level that qualified for these rewards. Once more we would like to thank everyone who supported the project and we hope that you enjoy your rewards. We hope to bring you an…

Today, we wanted to highlight more progress in a rapidly advancing area of medicine and talk about a new study that uses an exosomes-based approach for stroke treatment that repairs brain tissue. A stem cell-based approach to treating stroke Professor Steven Stice from the University of Georgia (UGA) and Nasrul Hoda of Augusta University led…

The SENS Research Foundation and the Forever Healthy Foundation have joined forces to host an exciting conference about rejuvenation biotechnology on March 15-17, 2018 at the Umspannwerk Alexanderplatz in Berlin, Germany. A conference for everyone The conference is open to the wider community interested in this field and anyone can attend. We believe that this…

Today, we would like to highlight a recent study in which researchers show a way to selectively accelerate bone regeneration. They have achieved this by delivering Jagged-1 to injuries instead of the bone morphogenetic proteins (BMPs) that have been traditionally used. What is jagged-1? Jagged-1 is an osteoinductive protein that activates the Notch signaling pathway,…

Researchers have created tiny DNA nanorobots that can deliver a protein payload that cuts off the blood supply to tumors in mice. DNA Origami According to a new study, the research team was able to create DNA nanorobots that can travel through the bloodstream, locate tumors, and deliver a protein that induces blood clotting, thus…

There may be other methods than drugs to destroy senescent cells, which accumulate with age. The immune system fails as we age, and rejuvenating it may be another route to removing harmful, pro-aging senescent cells. Senescent cells and senolytics As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent…

On 11th of February, the popular Futurist David Wood hosted a livestream about aging research on the London Futurists Youtube channel. The LEAF outreach director Elena Milova was one of the guests on the show, which was an informative summary of progress in the field of rejuvenation biotechnology. There were a range of guests included…

What if I told you that we could regenerate our teeth? Well, that may soon be a possibility thanks to new research showing that teeth can be encouraged to regrow. Rather than drilling holes into teeth and plugging them with artificial fillers, dentists in the near future may be able to rebuild your teeth with…

We wanted to bring your attention to an open-access publication in which the researchers suggest that the age-related decline of the thymus is more important than DNA mutation as a cancer risk factor[1]. Repairing the damage As we have discussed in this article, cancer is caused by DNA damage that creates mutations. Damage to our…

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