Today, as part of our series on the Hallmarks of Aging, we will be looking at the antagonistic hallmark of stem cell exhaustion. What are stem cells? As explained by an earlier article in this series, while every cell in your body has the same genetic code, regions of DNA are turned off and on…

According to a new study performed by University of Illinois researchers and published in Frontiers in Immunology, a diet rich in fiber reduces inflammation in aged mice, both in the guts and the brain. This beneficial reduction is due to high levels of butyrate, which result from the fermentation of fiber during digestion [1]. Study…

Today, we have an update from the MitoSENS team over at the SENS Research Foundation. As some of you may recall, MitoSENS was the first project we hosted on our research fundraising platform Lifespan.io back in August 2015. The project was successfully funded and raised $46,128, which was 153% of the funds needed. The extra…

One of the reasons why the idea of rejuvenating people isn’t all that easy to sell is that it challenges the status quo. For good or bad, we’re used to the fact that our health goes south on us as time goes by, ultimately killing us if nothing else does. That’s not a nice certainty…

According to a study led by scientists at Massachusetts General Hospital, exercise-induced neurogenesis improves cognition in a mouse model of Alzheimer’s disease, yielding more benefits than drug-induced adult neurogenesis. The scientists were able to figure out the difference between the two types of induced neurogenesis and pharmacologically reproduce the same benefits provided by exercise [1]….

Today, we want to let you know that the documentary Paywall: The Business of Scholarship is now available in both English and Russian. This is a documentary exploring the crisis in scientific journal publication and the excessive fees that some publishers charge to access knowledge. Holding scientific knowledge to ransom Around 70% of scientific publications…

Today, we are pleased to announce, at long last, that we will be launching a new project on the research fundraising platform Lifespan.io. The platform helps researchers to crowdfund projects focused on healthy longevity, and this new project is no exception. The David Sinclair Lab launches a new project on September 18th over at Lifespan.io…

According to a study by Georgia State University scientists, a molecule called β-hydroxybutyrate has anti-aging effects on the vascular system; more specifically, the molecule appears to prevent senescence of vascular cells by promoting cellular quiescence instead [1]. Study abstract β-hydroxybutyrate (β-HB) elevation during fasting or caloric restriction is believed to induce anti-aging effects and alleviate…

On September 11-14 in Basel, Switzerland, a new edition of the Basel Life congress will take place. As the name suggests, the event is entirely focused on the life sciences, and it aims to bring cutting-edge science and research closer to the general public as well as to give younger scientists an opportunity to to…

Today, we are going to take a look at the topic of NAD+, its precursor, nicotinamide mononucleotide, and the debate surrounding the ability of these molecules to pass through the cell membrane. What is NAD+? Nicotinamide adenine dinucleotide (NAD) is a coenzyme encountered in all living cells. It is a dinucleotide, which means that it…

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