The Journal Club on August 27 was hosted by Dr. Oliver Medvedik and special guest Dr. Alexander Tyshkovskiy, who works at the Gladyshev at Brigham and Women’s Hospital, Harvard Medical School, Boston. The topic was the recent paper “Identification and Application of Gene Expression Signatures Associated with Lifespan Extension” published in Cell Metabolism. This study…

Journal Club will be returning on August 27 with your host Dr. Oliver Medvedik and special guest Alexander Tyshkovskiy, a Ph.D. student who works at the Gladyshev at Brigham and Women’s Hospital, Harvard Medical School, Boston. The topic for the journal club this month will be the recent paper “Identification and Application of Gene Expression Signatures Associated…

The July journal club hosted by Dr. Oliver Medvedik looked at the recent SIRT6 evolutionary biology paper by Dr. Vera Gorbunova and collaborators, showing a relationship between enhanced SIRT6 function and longevity. The study took a deep dive into SIRT6 in multiple species and how it appears to support longevity to a lesser or greater extent…

The journal club hosted by Dr. Oliver Medvedik returns for July and takes a look at the new SIRT6 evolutionary biology paper by Dr. Vera Gorbunova and collaborators, showing a relationship between enhanced SIRT6 function and longevity. Join us at 13:00 EDT on our Facebook channel where we will be livestreaming the show and discussing this interesting…

For the June edition of Journal Club, Dr. Oliver Medvedik and guests took a look at the recent human trial of urolithin A, a metabolite produced by microflora and an active ingredient in pomegranates that is linked to increased levels of mitophagy in aged animals. Urolithin A is a byproduct created when bacteria in the…

For the June edition of Journal Club, Dr. Oliver Medvedik and guests will be taking a look at the recent human trial of Urolithin A, a metabolite produced by microflora and an active ingredient in pomegranates which is linked to increased levels of mitophagy in aged animals. Join us at 13:00 EDT on our Facebook channel where…

For the May Journal Club, Dr. Medvedik and guests took a look at the recent publication by the Spiegel Lab at Yale University where two forms of advanced glycation end products (AGEs) were successfully cleaved. We also covered this important breakthrough in our article – Reversal of Two Advanced Glycation End Products Achieved. Abstract Advanced glycation end products…

Hosted by Dr. Oliver Medvedik, the May edition of Journal Club will focus on the recent publication by the Spiegel Lab at Yale University where two forms of advanced glycation end products were successfully cleaved. We already discussed this important breakthrough in our article – Reversal of Two Advanced Glycation End Products Achieved. Now we…

For the April edition of the Journal Club, we discussed the recent paper from the Salk Institute. The findings, published in the journal Nature Medicine, showcase a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome. This treatment provides an important insight into the molecular pathways involved in accelerated aging,…

On April 30th at 13:00 EST the Journal Club will be discussing the recent paper from the Salk Institute. The findings, published in the journal Nature Medicine, showcase a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome. This treatment provides an important insight into the molecular pathways…

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