Vascular risk appears to be a strong predictor of dementia, especially in older individuals with high levels of brain beta-amyloids, and the interaction between these two risk factors might lead to a higher rate of cognitive decline, according to a recent study at the Massachusetts General Hospital. Alzheimer’s disease (AD) is an age-related neurological disorder…

Researchers from the University of Texas have discovered how NAD+ creation and consumption in cells is linked to glucose metabolism and their transformation from preadipocytes into adipocytes, or as most people know them, fat cells. INTRODUCTION Nicotinamide adenine dinucleotide (NAD) is an essential small molecule that is involved in a variety of physiological and pathological processes….

Researchers at Brown University have discovered a way to stimulate cellular autophagy, which is a natural recycling system built into every cell in the body. This has the potential to combat many age-related neurodegenerative diseases. What is autophagy? Autophagy means “eating of self” (from Ancient Greek “auto” = self, “phagein” = to devour). Autophagy is…

Researchers from the National Cancer Institute (NCI), the University of Kansas, and the National Center for Advancing Translational Science (NCATS) have discovered a compound that can block the spread of some types of cancer cells. Preventing cancer metastasis Metastasis is how cancer spreads from an initial site to a secondary site within the host’s body;…

Today, we wanted to bring your attention to a new review that takes an in-depth look at genomic instability, senescent cell accumulation, and its role in aging. DNA damage as a driver of aging Genomic instability, otherwise known as DNA damage, is thought by many researchers to be a primary reason why we age. Damage…

Professor George Church of Harvard Medical School has co-founded a new startup company, Rejuvenate Bio, which has plans to reverse aging in dogs as a way to market anti-aging therapies for our furry friends before bringing them to us. Dogs first, humans next The company has already carried some initial tests on beagles and plans…

On May 1, around 200 scientists from the Genome Project-write (GP-write) met in Boston and announced the first target of their project: the creation of cells that cannot be infected by viruses. What is the Genome Project-write? GP-write includes sub-projects like the Human Genome Project-write (HGP-write), which was formally announced on June 2, 2016, and…

A new study published by researchers at Western University and Lawson Health Research Institute has shown a link between the gut microbiome and atherosclerosis. During the study, the team examined blood levels of metabolic products in the gut microbiomes of 316 people from three groups: those with regular levels of plaque for their age, those…

A human study of the mitochondrial antioxidant MitoQ shows promise in addressing some aspects of vascular aging. Antioxidant-based therapeutics to forestall the effects of aging have had a long history, ever since the elaboration of the free radical theory of aging by Denham Harmon in 1956. However, this long history has also had mixed results,…

Today, we have an interview with Dr. Nichola Conlon, one of the speakers at the Undoing Aging 2018 Conference in Berlin, hosted by the Forever Healthy Foundation and SENS Research Foundation. Introducing Nuchido Dr. Conlon is the CEO of Nuchido, a new company that is set to launch later this year and was encouraged in…

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