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July 28th saw us run the third Journal Club, where we discussed a recent research publication. Journal Club is a monthly event livestreamed to our Facebook page and runs thanks to the support of our patrons – The Lifespan Heroes.

Unfortunately, we had some technical issues with this stream and could not broadcast it live as we usually do, so we recorded the show offline. In this episode we discuss the following paper:

Fulcher, L. J., Hutchinson, L. D., Macartney, T. J., Turnbull, C., & Sapkota, G. P. (2017). Targeting endogenous proteins for degradation through the affinity-directed protein missile system. Open Biology, 7(5), 170066.

https://www.ncbi.nlm.nih.gov/pubmed/28490657

We will be announcing the August Journal Club subject and date/time shortly. Thanks once again to the Lifespan Heroes for helping to make this possible. 

About the author
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Steve Hill

As a scientific writer and a devoted advocate of healthy longevity technologies Steve has provided the community with multiple educational articles, interviews and podcasts, helping the general public to better understand aging and the means to modify its dynamics. His materials can be found at H+ Magazine, Longevity reporter, Psychology Today and Singularity Weblog. He is a co-author of the book “Aging Prevention for All” – a guide for the general public exploring evidence-based means to extend healthy life (in press).
  1. August 3, 2017

    These videos are interesting to a biology window licker such as myself, but I don’t know if they will ever reach a wider audience.

    Any chance of producing a Youreka science style drawn video about AdPROM? e.g.

    https://www.youtube.com/watch?v=oMaiIyGfhQw

    Or do these videos take much more time and resources than I think? I did once have to make a video for a undergrad group project, which took a lot of time, but a lot of that was on the research itself and the setup.

    • mm
      August 4, 2017

      Jim, Journal Club is a technical and scientific club and its aimed at the biology window lickers as you so put it :)

      We are hoping to produce other video content in due course but Journal Club is absolutely for the hardcore.

  2. August 7, 2017

    Spherical Nucleic Acids with the gold nanoparticle in the middle removed and replaced with an enzyme have been successfully used to deliver a whole enzyme to cells.

  3. August 7, 2017

    DNA-Mediated Cellular Delivery of Functional Enzymes:

    https://pubs.acs.org/doi/abs/10.1021/jacs.5b09711

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