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July 28th saw us run the third Journal Club, where we discussed a recent research publication. Journal Club is a monthly event livestreamed to our Facebook page and runs thanks to the support of our patrons – The Lifespan Heroes.

Unfortunately, we had some technical issues with this stream and could not broadcast it live as we usually do, so we recorded the show offline. In this episode we discuss the following paper:

Fulcher, L. J., Hutchinson, L. D., Macartney, T. J., Turnbull, C., & Sapkota, G. P. (2017). Targeting endogenous proteins for degradation through the affinity-directed protein missile system. Open Biology, 7(5), 170066.

https://www.ncbi.nlm.nih.gov/pubmed/28490657

We will be announcing the August Journal Club subject and date/time shortly. Thanks once again to the Lifespan Heroes for helping to make this possible.

About the author

Steve Hill

Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 500 articles on the topic as well as attending various medical industry conferences. In 2019 he was listed in the top 100 journalists covering biomedicine and longevity research in the industry report – Top-100 Journalists covering advanced biomedicine and longevity created by the Aging Analytics Agency. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, and, Keep me Prime, and New Economy Magazine. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project. In 2015 he led the Major Mouse Testing Program (MMTP) for the International Longevity Alliance and in 2016 helped the team of the SENS Research Foundation to reach their goal for the OncoSENS campaign for cancer research.
  1. August 3, 2017

    These videos are interesting to a biology window licker such as myself, but I don’t know if they will ever reach a wider audience.

    Any chance of producing a Youreka science style drawn video about AdPROM? e.g.

    https://www.youtube.com/watch?v=oMaiIyGfhQw

    Or do these videos take much more time and resources than I think? I did once have to make a video for a undergrad group project, which took a lot of time, but a lot of that was on the research itself and the setup.

    • mm
      August 4, 2017

      Jim, Journal Club is a technical and scientific club and its aimed at the biology window lickers as you so put it :)

      We are hoping to produce other video content in due course but Journal Club is absolutely for the hardcore.

  2. August 7, 2017

    Spherical Nucleic Acids with the gold nanoparticle in the middle removed and replaced with an enzyme have been successfully used to deliver a whole enzyme to cells.

  3. August 7, 2017

    DNA-Mediated Cellular Delivery of Functional Enzymes:

    https://pubs.acs.org/doi/abs/10.1021/jacs.5b09711

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