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Today, we are delighted to announce that we have launched a new crowdfunding campaign on Lifespan.io: the NAD+ Mouse Project by Dr. David Sinclair and his team at Harvard Medical School.

NAD+ is a vitally important molecule that is found in every cell in your body and is involved in DNA repair, tissue growth, nutrient sensing and metabolism, cell-to-cell signaling, and many other cellular processes. Quite simply, without NAD+, cells would not work and life would be impossible. If you would like to learn more about NAD+ and its role in aging, check out our articles here, here, and here.

Can NMN Increase Longevity?

Может ли NMN продлить жизнь?

The new project proposes to conduct a lifespan study on normally aged mice to see if the NAD+ precursor nicotinamide mononucleotide (NMN) can increase lifespan. During the study, the mice will be observed to see if the molecule can delay age-related decline and if it improves the health and lifespan of the animals. This will provide researchers with important data to help support human studies with NMN, and this world-first study could provide valuable information.

The team will also be testing the effects of NMN by using a special kind of mouse called ICE (Induced Changes In Epigenome). ICE mice experience accelerated aging, so initial results will arrive more quickly and can be validated against the longer-term lifespan study in the regular-aging mice. With these mice, the team will be observing changes to behavior, physical activity, and other markers.

Finally, thanks to the generosity of two anonymous donors, the first $10,000 donated to the campaign will be matched twice, effectively tripling the value of your donations! The campaign is live right now, and remember, donations of any size can and do make a difference.

About the author

Steve Hill

As a scientific writer and a devoted advocate of healthy longevity and the technologies to promote them, Steve has provided the community with hundreds of educational articles, interviews, and podcasts, helping the general public to better understand aging and the means to modify its dynamics. His materials can be found at H+ Magazine, Longevity reporter, Psychology Today and Singularity Weblog. He is a co-author of the book “Aging Prevention for All” – a guide for the general public exploring evidence-based means to extend healthy life (in press).
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