We are very pleased to announce that Dr. Robert Shmookler Reis has joined the LEAF scientific advisory board. He studied at Harvard University (B.A.) and Sussex University (D.Phil.). He joined the University of Arkansas for Medical Sciences in 1980, where he holds the Udupa Chair of Gerontologic Research; he also serves as Affiliate Professor of Pathology at the Univ. of Washington in Seattle WA.

Dr. Robert Shmookler Reis is an expert in genetics whose work focuses on the molecular genetics of longevity and age-associated diseases and his team holds the world record for life extension in C. elegans (roundworms) making them live ten times their normal lifespan.

Protein aggregation in aging

His research team has recently been studying aggregates and their accumulation in relation to aging and the presence of certain proteins in neurodegenerative diseases. They also looked at aggregation in other tissues to see if it was a general feature of aging and it is, which aligns with the loss of proteostasis as described in the Hallmarks of aging. His team showed that a number of aggregates contribute to loss of muscle mass, he explains more in this short video about the recent study.

We look forward to seeing what the team discovers next and if they can develop therapies to prevent the formation of aggregates.

Dr. Robert Shmookler Reis is an advocate for basic research and believes that in order for us create effective strategies against aging we must invest not only in development but also in the basic science that improves our understanding of aging.


We are delighted to welcome Dr. Robert Shmookler Reis to our scientific advisory board and look forward to benefiting from his wealth of knowledge and expertise in genetics.


[1] Ayyadevara, S., Balasubramaniam, M., Suri, P., Mackintosh, S. G., Tackett, A. J., Sullivan, D. H., … & Dennis, R. A. (2016). Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY), 8(12), 3486.

About the author

Steve Hill

Steve serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 500 articles on the topic as well as attending various medical industry conferences. In 2019 he was listed in the top 100 journalists covering biomedicine and longevity research in the industry report – Top-100 Journalists covering advanced biomedicine and longevity created by the Aging Analytics Agency. His work has been featured in H+ magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, and, Keep me Prime, and New Economy Magazine. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project. In 2015 he led the Major Mouse Testing Program (MMTP) for the International Longevity Alliance and in 2016 helped the team of the SENS Research Foundation to reach their goal for the OncoSENS campaign for cancer research.
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