For the June edition of Journal Club, we will be taking a look at the recent paper entitled “Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver”.  We summarized the research in an article earlier this month. Summary Increasing evidence suggests that regulation of heterochromatin at the nuclear envelope underlies…

Researchers at the University of Virginia School of Medicine have discovered that as we age, our cells’ nuclear membranes become misshapen, which stops our genes from working properly. Nuclear membranes become distorted with age The DNA in all our cells is the same; however, the cells in our body show a great range of variation…

The Undoing Aging conference, a joint effort between the SENS Research Foundation and Michael Greve’s Forever Healthy Foundation, took place on March 15-17 in Berlin, gathering many aging researchers, advocates, investors, and other important members of the longevity community in one place. As we invited one of the best Russian journalists at educating the public…

In a new study, researchers at the Johns Hopkins Kimmel Cancer Center have shown that the epigenetic alterations associated with cancer evolve in an erratic manner during the early stages of tumor formation [1]. These tumor-associated epigenetic changes ultimately focus on a subset of genes that are also observed in aging. Cancer and senescent cells…

We have been talking about a number of new studies in past Journal Clubs, so we thought it was time to get into some aging theory. We chose to cover one of the most cited and highly regarded damage theories of aging in this edition of the club. In this edition of Journal Club, we…

The next Journal Club will be on October 31st at 13:00 EST/18:00 UK and will be streamed live from the Cooper Union, New York, to our Facebook page. The last episode we talked about the hallmarks of aging, a popular aging theory that places the various aging processes into of a number of damage categories (hallmarks) and proposes solutions…

This is the second part of our ongoing series of articles that discuss the Hallmarks of Aging. Published in 2013, the paper divides aging into a number of distinct categories (“hallmarks”) of damage to explain how the aging process works and how it causes age-related diseases[1]. Today, we will be looking at one of the…

We have been talking about a number of new studies in past Journal Clubs, so we thought it was time to get into some aging theory. We chose to cover one of the most cited and highly regarded damage theories of aging in this edition of the club. In this edition of Journal Club we…

So far, the only intervention that is known to consistently increase lifespan across multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of mouse strains tested[1] and many other species. The effects of CR have even been shown to influence how primates age and reduce the incidence of…

The next Journal Club will be on Tuesday, September 26th at 13:00 EST/18:00 UK and will be streamed live from the Cooper Union, New York, to our Facebook page. We have been talking about a number of new studies in past Journal Clubs, so we thought it was time to get into some aging theory. We have chosen to…

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