We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Today, we’re releasing a talk from Dr. Doug Ethell, who announced his company’s efforts to combat Alzheimer’s disease, describing where…

The macrophages resident in the brain and spinal cord appear to be a key element in the progression of Alzheimer’s disease, according to the results of a new mouse study. Microglial mayhem As we age, our immune cells become increasingly dysfunctional; once-helpful cells can behave in harmful ways, promoting persistent inflammation, impairing tissue regeneration, and…

In a recent study, a team of researchers has discovered that a naturally occurring protein called Lipocalin-type prostaglandin D synthase (L-PGDS) prevents, and can destroy, the protein aggregates associated with Alzheimer’s disease. Surprisingly common and with critical functions L-PGDS is a common protein, second only to albumin, in the human brain. It provides several critical…

In a recent study, a team from the Neurobiota Research Center in Korea has discovered that reducing gut dysbiosis partially alleviates the cognitive impairment associated with Alzheimer’s disease. This may seem puzzling, as the gut and the brain are separate and relatively distant organs, but this research makes sense in the context of chronic inflammation….

In a recent study, a group of researchers from Hebrew University-Hadassah Medical School, Feinberg School of Medicine, and Tel Aviv University examined astrocytes in mice and found that these cells exhibited a senescent phenotype that led to neurodegeneration and neurotoxicity [1]. Age-dependent increase in senescent astrocytes adjacent to Aβ plaques Cellular senescence, discovered in 1961…

A new mouse study highlights the proteins responsible for LC3-associated endocytosis (LANDO), an autophagy process that is involved in degrading β-amyloid, the principal substance associated with Alzheimer’s disease. Proteostasis Proteins in the human brain can form misfolded, non-functional, and toxic clumps known as aggregates. Preventing these aggregates from forming, and removing them when they do,…

On April 29th and 30th, the XPRIZE Foundation hosted an event at its headquarters in Culver City, California that could have a profound effect on the evolving landscape of biorejuvenation research: the Future of Longevity Impact Roadmap Lab. For those unfamiliar, the XPRIZE Foundation is famous for designing multi-million-dollar, global competitions to incentivize the development…

A recent article, published in the Oxford journal Brain, categorizes and draws attention to an age-related disease that impacts the brain yet is widely unknown, even among scientists: limbic-predominant age-related TDP-43 encephalopathy (LATE) [1]. The symptoms of this disease are similar to those of Alzheimer’s disease. It causes cognitive impairment and, when presenting alongside Alzheimer’s…

A team of Stanford researchers led by Professor Wyss-Coray set out to find out which genes were linked to age-related cognitive decline. Not only did the researchers find the culprit, they were able to reverse cognitive decline and rejuvenate aged mouse brains. Searching for the cause of cognitive decline Microglia are immune cells that reside…

The complex relationship between the microbiome and the rest of the body has only recently started to become truly appreciated. The bacteria of the gut are increasingly looking like a potential player in aging, and some bacteria in the mouth associated with chronic periodontitis may be linked to Alzheimer’s disease [1]. University of Louisville researcher…

© 2018 - LIFE EXTENSION ADVOCACY FOUNDATION
Privacy Policy / Terms Of Use

       Powered by MMD