A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells (CSCs) of the breast [1]. While antibiotics are not normally effective against cancer, and Vitamin C is more well-known for its role in supporting the…

Researchers from Scripps Research have discovered how the proteasome, which is made of protein complexes in the cell that breaks down damaged and unwanted proteins, converts energy into motion to unfold target proteins for recycling. What is the proteasome? The proteasome is a protein complex whose job is to break down and recycle proteins that…

An open-access paper published in Nature Communications sheds light on how an accumulation of α-synuclein protein in brain cells contributes to causing Parkinson’s disease. In particular, the researchers discovered how clumps of the protein damage important proteins on mitochondrial surfaces, leading to impaired energy production, swelling and bursting of the mitochondria themselves, and, ultimately, cell…

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