A recent study suggests that circulating glucuronic acid may be a useful predictor of both lifespan and healthspan in humans and mice. What is glucuronic acid? Glucuronic acid is a metabolite of glucose and is critical for the detoxification of xenobiotic substances. These are compounds that are not naturally produced, should not normally be in…

At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge. BioAge is developing a drug discovery platform that uses machine learning and artificial intelligence to discover targets that have the potential to promote healthy lifespan (healthspan) by slowing…

Today, we’re offering another talk from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. In her talk, Morgan Levine of the Yale School of Medicine discussed epigenetic biomarkers in detail, discussing the ways in…

A new clock that analyzes the age of the immune system may be the next big thing in aging biomarkers. Measuring the age of your immune system As we age, our immune systems begin to decline due to many factors, including the thymus shrinking and producing ever-fewer T cells, the ever-increasing chronic inflammation called “inflammaging”,…

In a new study [1], researchers have identified the reason why cells become defective when they grow too large and why protein creation fails when cells grow larger than their original healthy size, as is typically seen in aged and senescent cells. They demonstrate that in enlarged yeast and human cells, RNA and protein biosynthesis…

In aging research, there has long been a need for better biomarkers that can detect and confirm the presence of senescent cells. This has become particularly urgent in recent years due to the meteoric rise of the senescent cell-clearing therapies known as senolytics. Traditional ways of measuring senescent cell populations are problematic and have multiple…

The MouseAge project was launched last year after successful fundraising on Lifespan.io. It aimed to develop the first photographic biomarker of aging in mice to help researchers assess potential anti-aging therapies, reduce animal testing, and speed up the pace of aging research. The major advantage of this approach as opposed to other biomarkers of aging,…

A new aging clock developed by Professor Steve Horvath and his research team takes measuring your biological age a step further and can accurately predict your future lifespan. The epigenetic clock As we age, our DNA experiences chemical changes called DNA methylation (DNAm); these changes are used as a way to measure age and are…

The bacteria in your gut may offer an accurate way to measure your biological age, according to a new study. The microbiome In recent years, it has become increasingly apparent that the communities of bacteria, fungi, and other microbes living in our gut, known as the microbiome, are likely involved in aging, particularly the chronic…

The AgeMeter has been selected as an exhibit at the Consumer Electronics Show (CES) at the Eureka Park new technology area at the Sands Expo in Las Vegas, Nevada on Jan 8-11. The AgeMeter is a functional aging biomarker system that can be used to monitor how someone is aging, and it was successfully funded…

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