A type of artificial intelligence technique is now being used to develop new drugs and therapies and could perhaps even help to solve aging. An urgent need for aging biomarkers There has long been an urgent need in our field to develop increasingly accurate biomarkers of aging so that the efficacy of interventions can be…

A team of researchers, including Drs. Vadim Gladyshev and Steve Horvath, recently published a review of DNA methylation aging clocks, which use biomarkers to determine the biological age of a person. Aging causes epigenetic alterations to occur, including changes to DNA methylation, histone modification, transcriptional alterations (variance in gene expression), and remodeling of chromatin (a…

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Vadim Gladyshev of Harvard Medical School discussed methods of discovering longevity interventions, including analyzing the genomes of long-lived mammals and…

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Dr. Peter Fedichev, co-founder of GERO, discussed biomarkers in the context of mouse research, particularly physiological frailty and blood cell…

We’re continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Dr. Qingsong Zhu, the COO of Insilico Medicine, discussed the use of deep learning in creating biomarkers for aging. Initially…

A recent study suggests that circulating glucuronic acid may be a useful predictor of both lifespan and healthspan in humans and mice. What is glucuronic acid? Glucuronic acid is a metabolite of glucose and is critical for the detoxification of xenobiotic substances. These are compounds that are not naturally produced, should not normally be in…

At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge. BioAge is developing a drug discovery platform that uses machine learning and artificial intelligence to discover targets that have the potential to promote healthy lifespan (healthspan) by slowing…

At the Ending Age-Related Diseases 2019 conference, Dr. Micheal Lustgarten discussed the role of the gut microbiome in older adults, explaining that gut flora affect muscle strength and analyzing the species present in their native microbiome colonies. He also discussed Aging.ai and the blood chemistry of aging people, including albumin and micronutrients.

Today, we’re offering another talk from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. In her talk, Morgan Levine of the Yale School of Medicine discussed epigenetic biomarkers in detail, discussing the ways in…

A new clock that analyzes the age of the immune system may be the next big thing in aging biomarkers. Measuring the age of your immune system As we age, our immune systems begin to decline due to many factors, including the thymus shrinking and producing ever-fewer T cells, the ever-increasing chronic inflammation called “inflammaging”,…

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