Cancer can often evade the immune system by sending signals that fool it into thinking that the cancer cells are normal, healthy cells and that it should ignore them. Earlier this year, we reported on an approach to treating cancer in which the immune system can be taught to detect cancer by seeing past the…

T Cells are a major component of the formidable immune system that the body keeps at the ready to respond to the first sign of infection or disease. T cells detect if cells have been infected with a virus; upon detection, they trigger these cells’ ablation and destroy the virus. Unfortunately, the T cells do…

Natural killer (NK) cells are lymphocytes, immune cells which have a powerful arsenal of cytotoxic weaponry that they can use against tumors. Unfortunately, tumors protect themselves using a protective microenvironment that shields them from attack from NK cells. This microenvironment promotes tumor growth and survival and has an immunosuppressive effect that blunts the attempts of…

Changes to the microbiome in the gut may explain why related conditions are linked to different risk levels and types of gastric tumors, according to a new study. What are the microbiota and microbiome? The microbiota is an “ecological community of commensal, symbiotic and pathogenic microorganisms” found in and on all multicellular organisms. A microbiota…

A research team at MIT has used synthetic biology to create a gene circuit that triggers the immune system to attack cancer when it first detects the signs of the disease. The circuit works by only activating the immune response when two specific cancer biomarkers are detected. The new study was published in the journal…

The use of artificial intelligence and, in particular, machine learning is becoming increasingly popular in research. These systems excel at high-speed data analysis, interpretation, and laborious research tasks, such as image assessment. One of the areas in which machine learning has been enjoying success is image recognition. Now, researchers have begun to use machine learning…

By treating one of the root causes of aging – senescent cells – a new class of drugs, known as senolytics, has the potential to treat a wide range of age-related diseases rather than the traditional approach of dealing with them one at a time.  Today we are going to take a look at what…

Today we have a new study where researchers have created immune cells that ignore the way cancer tries to hide from detection. Hiding in plain sight Macrophages are one of the types of immune cell and are responsible for dealing with dangerous cells, such as those which have become cancerous. The problem is, most cancer…

Oisin Biotechnologies is a rejuvenation biotechnology company which received its seed funding from the Methuselah Foundation and SENS Research Foundation a few years ago. The current focus of Oisin is the targeted clearance of senescent cells, using drugs sometimes referred to as senolytics. Senescent cells are one of the hallmarks of aging, and as they…

Cancer is predominantly a disease of aging caused by genomic instability. Finding effective ways to prevent and treat cancer is therefore of great interest to those working in the field of aging research as well as those working in oncology.  Therapies that target combinations of neoantigens, distinctive markers on the surface of cancer cells that…

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