Researchers at Harvard have described a new cancer vaccine approach that uses an injectable biomaterial scaffold to deliver a payload of tumor-specific peptides that stimulate the immune system to respond rapidly to cancer cells. Abstract Existing strategies to enhance peptide immunogenicity for cancer vaccination generally require direct peptide alteration, which, beyond practical issues, may impact…

Some cancer cells express some of the same genes that senescent cells do, so it makes sense that drugs that destroy senescent cells may also destroy cancer cells. This was what the researchers in this new study set out to test. Abstract p16Ink4a is a potent cell cycle inhibitor engaged to support cell cycle arrest…

In a new study, researchers at the Johns Hopkins Kimmel Cancer Center have shown that the epigenetic alterations associated with cancer evolve in an erratic manner during the early stages of tumor formation [1]. These tumor-associated epigenetic changes ultimately focus on a subset of genes that are also observed in aging. Cancer and senescent cells…

Researchers have created tiny DNA nanorobots that can deliver a protein payload that cuts off the blood supply to tumors in mice. DNA Origami According to a new study, the research team was able to create DNA nanorobots that can travel through the bloodstream, locate tumors, and deliver a protein that induces blood clotting, thus…

Last year, we talked about a new cancer “vaccine” currently in clinical trials in an article here, and now a second cancer vaccine is capturing media interest due to impressive results in the lab. The new therapy is now in human clinical trials for lymphoma patients. Researchers at Stanford Medicine have found that injecting two…

Thirty-seven-year-old Nick Asoian of Denver unsuccessfully fought Hodgkin’s Lymphoma using conventional cancer treatments for two years.  In 2008, while in New Zealand for a ski race, Nick was diagnosed with the condition. Two bone marrow transplants and two years of chemotherapy combined with radiation therapy didn’t bring his cancer to heel. Nick Asoian. Image source:…

Novel therapeutic approaches may often require quite a bit of lateral thinking, as researchers at the Salk Institute have recently shown in a study presenting a novel method to interfere with cancer growth. The problem with cancer In a nutshell, the reason cancer is such an insidious enemy is that its cells divide uncontrollably, leading…

By now, the immunotherapeutic approach to fighting cancer has become so popular that you’ve most probably already heard of it—we’ve discussed it a few times too.  While immunotherapy is currently one of the best weapons in our anticancer arsenal, it is not always effective; however, researchers at Zurich University have recently found a way to…

Researchers have demonstrated how alcohol damages mouse stem cell DNA in a new study, helping to explain why drinking can increase cancer risk[1]. The study was published in the journal Nature on January 3. There have been multiple cell culture studies looking at how alcohol promotes cancer, but this study used mice to show how…

Cancer can often evade the immune system by sending signals that fool it into thinking that the cancer cells are normal, healthy cells and that it should ignore them. Earlier this year, we reported on an approach to treating cancer in which the immune system can be taught to detect cancer by seeing past the…

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