Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why we age, develop diseases such as diabetes, and suffer from stiffened arteries and hypertension. In the business of startups, a seed round refers to a…

The results of a small human clinical trial focused on skin aging have been published, and they are positive. A topical application of rapamycin, an FDA-approved drug that is used to combat organ rejection during donor transplants and targets the mechanistic target of rapamycin (mTOR) pathway, was tested to see if it had any effect…

Researchers from North Carolina State University have demonstrated that exosomes harvested from human skin cells can repair sun-damaged skin cells in mice. The therapy also appears to be more effective than retinol and stem cell treatment, and best of all, delivery of the therapy is needle-free. What are exosomes? Exosomes are essentially membrane-wrapped packages that…

At the Eurosymposium on Healthy Ageing, we had the opportunity to interview Sven Bulterijs of the Healthy Life Extension Society (HEALES). Some of our regular readers may recall seeing Sven join us for some of the monthly episodes of the Journal Club and he is an active figure in the rejuvenation biotechnology field.  During the…

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