For the first time in an animal model, researchers at the Lewis Katz School of Medicine at Temple University showed that the tau pathology that accompanies Alzheimer’s disease can be reversed using the asthma drug zileuton [1]. Abstract Previous studies showed that the leukotrienes pathway is increased in human tauopathy and that its manipulation may…

New research from the University of Southern California has shed light on how the decline of the brain’s vascular system precedes the build-up of the plaques and tau tangles associated with Alzheimer’s disease. A leaky blood-brain barrier sets the scene for dementia Traditionally, many researchers have focused their efforts on the amyloid and tau proteins…

Researcher Dr. Dena Dubal, from the University of California San Francisco, is considering a new approach to combat neurodegenerative diseases, such as Alzheimer’s disease and dementia, using a protein known as klotho. Aging is the foundation of age-related diseases Instead of trying to understand each of these diseases and the complex mechanisms unique to both,…

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