Researchers at the University of Helsinki have shown why the regenerative capacity of the cells lining the intestines declines with age and that targeting a particular enzyme can restore the regenerative potential of this tissue. Notum blocks the Wnt pathway During normal function, the cells of the intestinal epithelium, a single cell layer that forms…

The role that the gut microbiome plays in aging is increasingly being appreciated in the research world as more evidence arrives to support it. A new publication reviews the various supporting evidence and takes a look at the gut microbiome in the context of poor diets and how they may facilitate the progression of dysbiosis…

A new study has outlined the age-related changes of the gut microbiome, showing a correlation between the microbiome’s composition and overall health. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our gut. The four bacterial phyla of Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria comprise 98% of the…

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