A study on animals with autoimmune myocarditis was recently released in the journal Cell Reports [1], showing the impact of heart inflammation on the types of immune cell that are formed in the heart. This could have a significant impact on our understanding of cardiac aging. What is myocarditis and how is it relevant to…

In a new study, researchers show that the presence of senescent cells is an important contributor to aging of the cardiovascular system, particularly the heart [1]. Senescent cells and senolytics As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissues of…

Researchers at Newcastle University have shown that clearing out senescent cardiac muscle cells from the hearts of aged mice restores heart health. It seems that not a month goes by without a new study showing that senolytics, drugs that remove aged and damaged cells from the body, improve organ or tissue function by reversing some…

Today, we want to highlight a study that shows the link between atherosclerosis and the age-related shrinking of the thymus, which is arguably the most important organ of the immune system [1]. The adaptive and innate immune systems and atherosclerosis The thymus is essentially like an army base where new T cells develop and are…

Researchers from Washington University School of Medicine in St. Louis have discovered that a particular type of immune cell encourages harmful inflammation in the heart after a heart attack, and they have found a potential solution for protecting the heart. The study, which was led by Dr. Douglas L. Mann, showed that a mouse model…

Hypertension is an increasingly encountered condition in modern society, as sedentary lifestyles, poor diet, and other unhealthy lifestyle choices are becoming more prevalent. The aging processes generally cause our blood pressure to rise, as they steadily clog our arteries, stiffen blood vessels, and cause our hearts to work harder to get blood to all our…

Researchers at the University of California San Diego School of Medicine have shown that they can block inflammation in mice, thereby protecting them from liver disease and hardening of the arteries while increasing their healthy lifespan. The study, published in the journal Nature, shows that inflammation can be blocked using a naturally occurring antibody that…

Atherosclerosis is the number one killer in the world, and science is working on solutions to combat this age-related disease. A new mouse study has shown that the drug trodusquemine can melt away the accumulated arterial plaques that lead to heart attacks and strokes. What is Atherosclerosis? Atherosclerosis is an age-related disease in which toxic,…

A new study has shown that it is possible to reverse the scarring that forms after a heart attack, turning it back into healthy heart tissue. The researchers demonstrated that they can change fibroblasts (scar tissue cells) into cardiomyocytes (heart muscle cells), though getting to the bottom of how this happens has been a challenge….

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