The levels of circulating inflammatory cytokines and other signaling factors increase with age, contributing to the loss of tissue maintenance, wound healing difficulties, immune system dysfunction, loss of stem cell mobility and a host of other problems. However, it remains a subject of much debate as to what starts the cascade of inflammation that drives…

The link between inflammation, cellular senescence, aging, and cancer is a complex relationship, but a new study sheds light on how these four interact. The light and dark side of inflammation and cellular senescence Cellular senescence is a protective mechanism that helps us to stay healthy and avoid cancer by removing damaged and aged cells…

The thymus gland is located at the top of the breastbone and is where the majority of T cells are produced by the immune system. One can think of the thymus as being like an army camp where new soldiers are trained and given their weapons to fight invading forces; in this case, the T…

Many of us have experienced the uphill struggle to control our weight as we get older. We cannot eat whatever we like and stay slim like when we were younger, our holiday indulgences refusing to go away. The battle of the bulge gets harder the older we get, and there was little we could do…

A new mouse study by University of Florida Health researchers shows that multiple sclerosis can be inhibited or even reversed by using a gene therapy that stops the immune response caused by the disease in its tracks. What is multiple sclerosis? Multiple sclerosis (MS) is an autoimmune disease, affects around 2.3 million people worldwide and…

The immune system is like an army keeping us safe from invasion, injury and infection and helps us to regenerate and repair tissues and organs. However, the immune system is sometimes a double-edged sword that does more harm than good. A lot of focus has been on the role of macrophages and their ability to…

One of the most intriguing questions in biology discusses why some animals can regenerate their major body parts, such as hearts and limbs, and others cannot. A new study led by Dr. James Godwin from the MDI Biological Laboratory suggests that the innate immune system could be the answer. Secrets revealed in salamander study A…

The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by a system that is always present across the body, while the adaptive immune response appears only in response to an infection and is always specific…

An interesting new study has demonstrated a method to reprogram specific T cells. Much like researchers have been experimenting recently with macrophages and making them change into an anti-inflammatory rather than a proinflammatory type, the team here has achieved similar results with T cells. As we age, the immune system becomes dysfunctional, either due to…

This may seem to be obvious, but blood is made from many things. Blood plasma, for instance, is mostly made of water, carrying proteins and cells, along with various chemicals diluted within the plasma or bound to proteins. For instance, sodium bicarbonate – baking soda – is, in fact, a vital chemical that our bodies…

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