New research suggests that senolytic drugs, which remove harmful senescent cells that accumulate during aging, may be an effective therapy for glaucoma, a common age-related condition that leads to loss of vision. In the short term, inflammation serves a useful purpose, as it helps to spur the repair and regeneration of tissue and rallies the…

A new paper on senescent cells and aging brings together the current knowledge on the subject and presents it in a handy review format. What are senescent cells? As you age, increasing numbers of your cells enter into a state known as senescence. Senescent cells do not divide or support the tissues of which they…

In a recent study, a team from the Neurobiota Research Center in Korea has discovered that reducing gut dysbiosis partially alleviates the cognitive impairment associated with Alzheimer’s disease. This may seem puzzling, as the gut and the brain are separate and relatively distant organs, but this research makes sense in the context of chronic inflammation….

A new study has discovered that the guts of elite athletes contain a particular type of bacteria that boosts exercise capacity. The bacteria are members of the genus Veillonella and are not present in the gut microbiomes of sedentary people. The microbiome The microbiome is an ever-changing ecosystem in the gut populated by a vast…

The gut microbiome appears to be increasingly responsible for at least some of the decline of the immune system during aging, and a new mouse study shows that it is reversible. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our guts. The four bacterial phyla of…

In a new study, researchers at the University of Pécs, Hungary used cell secretions known as exosomes to regenerate the thymus, one of the most important organs in the body. The thymus shrinks as we age The thymus is arguably one of the most critical organs in the body, and it is where new T…

A recent study has outlined the relationship between B cells, atherosclerosis, and the transcription factor c-Myb. While this factor is necessary for hematopoiesis, the formation of new blood cells, it has been shown to affect B cells, a type of lymphocyte, in a way that makes atherosclerosis more severe. A new look at inflammaging Inflammation…

The skin is our first line of defense against invading pathogens, and scientists at UC San Francisco and the San Francisco Veterans Administration (VA) Health Care System believe that it may be a cause of inflammaging, the age-related chronic inflammation that encourages a number of age-related diseases to develop. As we age, we generally experience…

Scientists from the A*STAR Singapore Immunology Network have discovered that immune cells called nonclassical monocytes undergo cellular senescence, contradicting what was previously thought of them [1]. Abstract Human primary monocytes comprise a heterogeneous population that can be classified into three subsets based on CD14 and CD16 expression: classical (CD14high/CD16−), intermediate (CD14high/CD16+), and non-classical (CD14low/CD16+). The…

Today, we want to draw your attention to a new study that looks at the role of chronic age-related inflammation and the decline of nerve regeneration. Inflammaging drives age-related loss of tissue regeneration Inflammation can be beneficial and serves an important purpose: it spurs regeneration and immune responses while combating pathogens and other invaders. This…

© 2020 - LIFE EXTENSION ADVOCACY FOUNDATION
Privacy Policy / Terms Of Use

       Powered by MMD