A recent study suggests that circulating glucuronic acid may be a useful predictor of both lifespan and healthspan in humans and mice. What is glucuronic acid? Glucuronic acid is a metabolite of glucose and is critical for the detoxification of xenobiotic substances. These are compounds that are not naturally produced, should not normally be in…

A role for the gut microbiome on the health and functioning of many tissues, including the brain, liver, kidney, and adiposity, has been widely reported in the literature. Interestingly, 2019 might be the year that the role of the gut microbiome on skeletal muscle (i.e. the gut-muscle axis) comes into greater focus. The influence of…

In a recent study, a team from the Neurobiota Research Center in Korea has discovered that reducing gut dysbiosis partially alleviates the cognitive impairment associated with Alzheimer’s disease. This may seem puzzling, as the gut and the brain are separate and relatively distant organs, but this research makes sense in the context of chronic inflammation….

Today, we want to highlight a recent study in which a team of researchers from UT Southwestern demonstrates how adjusting the gut microbiome in mice lowers the occurrence of cancer. What is the gut microbiome? The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our gut. The four bacterial phyla…

A new study has discovered that the guts of elite athletes contain a particular type of bacteria that boosts exercise capacity. The bacteria are members of the genus Veillonella and are not present in the gut microbiomes of sedentary people. The microbiome The microbiome is an ever-changing ecosystem in the gut populated by a vast…

In a small, recent human trial, a naturally occurring compound called urolithin A has yielded positive results and appears to slow down part of the aging process that is related to the production of energy in our cells. What is urolithin A? Urolithin A is the end product created when bacteria in the gut break…

The gut microbiome appears to be increasingly responsible for at least some of the decline of the immune system during aging, and a new mouse study shows that it is reversible. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our guts. The four bacterial phyla of…

The role that the gut microbiome plays in aging is increasingly being appreciated in the research world as more evidence arrives to support it. A new publication reviews the various supporting evidence and takes a look at the gut microbiome in the context of poor diets and how they may facilitate the progression of dysbiosis…

Earlier this year, we launched a new webinar series where our monthly patrons, the Lifespan Heroes, are given the opportunity to join live discussion panels with the researchers who are working on solving aging. Our April 8th, 2019 episode saw Dr. Mike Lustgarten, Dr. Amy Proal, and Dr. Cosmo Mielke join hosts Dr. Oliver Medvedik…

A new publication from researchers at the University of Colorado Boulder shows how gut bacteria increase the risk of cardiovascular disease by contributing to the stiffening of the blood vessels during aging. This study is the first to demonstrate that changes to the gut microbiome promote vascular aging and harm health [1]. The researchers treated…

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