A new publication from researchers at the University of Colorado Boulder shows how gut bacteria increase the risk of cardiovascular disease by contributing to the stiffening of the blood vessels during aging. This study is the first to demonstrate that changes to the gut microbiome promote vascular aging and harm health [1]. The researchers treated…

On Monday, April 8th, we will be hosting our second Lifespan.io webinar, during which we will be discussing the microbiome and its role in aging and disease. Our second research webinar Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, so to thank them we have launched a new…

A new study has outlined the age-related changes of the gut microbiome, showing a correlation between the microbiome’s composition and overall health. The gut microbiome The microbiome describes a varied community of bacteria, archaea, eukarya, and viruses that inhabit our gut. The four bacterial phyla of Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria comprise 98% of the…

The bacteria in your gut may offer an accurate way to measure your biological age, according to a new study. The microbiome In recent years, it has become increasingly apparent that the communities of bacteria, fungi, and other microbes living in our gut, known as the microbiome, are likely involved in aging, particularly the chronic…

Researchers from the Kapahi Lab at the Buck Institute for Research on Aging have shown in a new study that increased intestinal permeability is caused by the age-related loss of epithelial cells that form the gut membrane [1]. As we age, the integrity of the gut membrane declines, and it becomes more permeable; this is…

Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome in pathological conditions. However, unlike germ-free mice, the effects…

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