Shift Bioscience is a company aiming to solve the problem of mitochondrial dysfunction, one of the hallmarks of aging, by repairing the aging mitochondria in our cells so that they work as if they were younger. Mitochondrial dysfunction is at the heart of aging The mitochondria are often called the powerhouses of cells, and they…

Exercise really does influence how we age, and a new study shows how regular exercise in later life can help offset the decline of NAD+ and NAMPT, two important molecules that facilitate cellular energy production, in skeletal muscle. NAD+ and mitochondria The mitochondria are the power stations of the cell and provide the energy that…

For the June edition of Journal Club, Dr. Oliver Medvedik and guests took a look at the recent human trial of urolithin A, a metabolite produced by microflora and an active ingredient in pomegranates that is linked to increased levels of mitophagy in aged animals. Urolithin A is a byproduct created when bacteria in the…

A new open-access study from researchers at the Biomedical Research Centre in the United Kingdom shows how two antibiotics and Vitamin C can be combined to suppress cancer stem cells (CSCs) of the breast [1]. While antibiotics are not normally effective against cancer, and Vitamin C is more well-known for its role in supporting the…

A recent study has suggested that A.Ceratii, a parasite that feeds on small life forms, including the ones that form algal blooms, contains mitochondria that have no mitochondrial DNA, and at least some of this DNA is found in the parasite’s own genetic code. However, a few genes found in humans are missing and replaced…

Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, and this year, we will be showing our appreciation for that support with the launch of a brand new initiative – our new webinar series where you can meet the scientists working on the solutions to aging and age-related diseases….

Today, we will be covering another important root cause of aging, mitochondrial dysfunction, which is one of the Hallmarks of Aging [1]. What are mitochondria? Mitochondria, which are often called the powerhouses of cells, act like miniature factories, converting the food we eat into usable energy in the form of a chemical called adenosine triphosphate…

Today, we have an update from the MitoSENS team over at the SENS Research Foundation. As some of you may recall, MitoSENS was the first project we hosted on our research fundraising platform Lifespan.io back in August 2015. The project was successfully funded and raised $46,128, which was 153% of the funds needed. The extra…

In a new study, researchers have identified a direct link between mitophagy and inflammation. Aging is accompanied by rising levels of oxidative stress, which is primarily caused by our cellular power plants, the mitochondria. As we age, our mitochondria start to produce an increasing amount of oxidized molecules known as reactive oxygen species (ROS), which…

Credit: Shutterstock.com

Today, we will be taking a look at a new study showing that an NAD+ precursor was able to improve mitochondrial function in cells and flies with a model of Parkinson’s disease. Summary While mitochondrial dysfunction is emerging as key in Parkinson’s disease (PD), a central question remains whether mitochondria are actual disease drivers and…

© 2018 - LIFE EXTENSION ADVOCACY FOUNDATION
Privacy Policy / Terms Of Use

       Powered by MMD