The MitoMouse campaign has ended, and what a final few days it has been! Thanks to the efforts of the community, an amazing total of $77,525 has been raised in support of this mitochondrial repair project of the SENS Research Foundation. There were 319 people who backed the project and helped to make this the…

Wonderful news today: the MitoMouse project has reached its first stretch goal, and the research will now have even more scope thanks to the efforts of the community. We would like to thank Anthony Jennings, Jose Almeida, Daria Khaltourina, Max Twemlow, Denis Dmitriev, Daniel Smith, and Ingrid Wolf for helping us to hit the first stretch…

Good news for the MitoMouse project! Thanks to the support of the community, LongeCity has already agreed to donate several thousand dollars to the MitoMouse campaign. It plans to expand this support, fully funding the stretch goal of $75,000 if we are able to reach the first $65,000 goal. With just $1460 left to go…

On Friday, October 25, we hosted a Q&A webinar with the team behind MitoMouse, the second MitoSENS program that we are funding. In this webinar, Drs. Aubrey de Grey, Amutha Boominathan, and Matthew “Oki” O’Connor answered viewer questions about the nature of their research and the SENS approach to age-related disease. There are only a…

Wonderful news: the MitoMouse project has successfully reached its initial $50k goal and is well on the way towards the first stretch goal! This means that the project will launch at the lab and the MitoMouse strain will be created. The next step for this ambitious project is to actually create progeny from the SickMice and…

GenSight Biologics has recently released data showing the effectiveness of GS010, the company’s gene therapy for Leber Hereditary Optic Neuropathy (LHON), a mitochondrial disease that can lead to blindness. Like in previous studies, this therapy had a bilateral effect. Gene Therapy In LHON, the mitochondrial protein ND4 is poorly expressed through mitochondrial DNA (mtDNA). GS010…

Back in January, we were joined by Dr. Aubrey de Grey, Dr. Amutha Boominathan, Dr. Matthew O’Conner, and Michael Rae from the SENS Research Foundation for a webinar discussion panel focused on MitoSENS, the mitochondrial repair program. During the webinar, a number of points were discussed, and the Lifespan Heroes in the audience got to…

We recently had the opportunity to interview Dr. Amutha Boominathan from the SENS Research Foundation, at the Ending Age-Related Diseases 2019 conference about her research on mitochondrial repair therapies, the value of animal models, and her views on the future of aging research. Dr. Amutha Boominathan received both her MSc and her PhD in Biochemistry from…

Today, we have launched the MitoMouse project on our fundraising platform Lifespan.io. This project aims to reverse the damage that aging does to the mitochondrial DNA and to restore energy production in our cells with the goal of preventing age-related ill health. The power stations of the cell The mitochondria are the power stations of…

Shift Bioscience is a company aiming to solve the problem of mitochondrial dysfunction, one of the hallmarks of aging, by repairing the aging mitochondria in our cells so that they work as if they were younger. Mitochondrial dysfunction is at the heart of aging The mitochondria are often called the powerhouses of cells, and they…

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