The March Journal Club hosted by Dr. Oliver Medvedik focused on a recent study that showed transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. These findings support the idea that cognitive decline is in part due to the aging of blood cells,…

On Monday, April 8th, we will be hosting our second Lifespan.io webinar, during which we will be discussing the microbiome and its role in aging and disease. Our second research webinar Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, so to thank them we have launched a new…

For the January Journal Club, we will be taking a look at the recent human senolytics trial conducted at the Mayo Clinic. Abstract Background Cellular senescence is a key mechanism that drives age-related diseases, but has yet to be targeted therapeutically in humans. Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal cellular senescence-associated disease. Selectively…

Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, and this year, we will be showing our appreciation for that support with the launch of a brand new initiative – our new webinar series where you can meet the scientists working on the solutions to aging and age-related diseases….

Tau protein aggregation is associated with cellular senescence in the brain is the topic for the November Journal Club. This is an important paper as it shows how senescent cells contribute to Alzheimer’s disease and how removing them appears to improve the condition. We will see you live on our Facebook page at 13:00 EST for…

We recently did an Ask Me Anything (AMA) event on our Facebook page. We get a lot of questions about our work, many of which are frequent, so we decided that this popular format would be the best way to answer them. The panel featured LEAF Board Directors Keith Comito, Dr. Oliver Medvedik, Elena Milova,…

Earlier this year, we hosted the Ending Age-Related Diseases 2018 conference at the Cooper Union in New York City. This conference was designed to bring together the best in the aging research and biotech investment worlds and saw a range of industry experts sharing their insights. Dr. Oliver Medvedik, LEAF vice president and Director of…

The October Journal Club will be focusing on a new study in worms where a combination of compounds acted in synergy to almost double lifespan. SUMMARY There is growing interest in pharmacological interventions directly targeting the aging process. Pharmacological interventions against aging should be efficacious when started in adults and, ideally, repurpose existing drugs. We…

This month, we decided to do the Journal Club a bit earlier than usual to coincide with the launch of the NAD+ Mouse Project over at Lifespan.io. As the project is testing to see if NAD+ repletion increases lifespan, we thought that it would be an ideal time to explore NAD+ biology and take a…

Today, we have another video from our Ending Age-Related Diseases 2018 conference. This particular video shows one of our panels, “The Current State of Aging Research”, which featured Dr. Aubrey de Grey of the SENS Research Foundation, Dr. Vadim Gladyshev of Harvard Medical School, Dr. Oliver Medvedik of Lifespan.io and the Cooper Union, and Steven…

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