Hosted by Dr. Oliver Medvedik, the May edition of Journal Club will focus on the recent publication by the Spiegel Lab at Yale University where two forms of advanced glycation end products were successfully cleaved. We already discussed this important breakthrough in our article – Reversal of Two Advanced Glycation End Products Achieved. Now we…

Earlier this year, we launched a new webinar series where our monthly patrons, the Lifespan Heroes, are given the opportunity to join live discussion panels with the researchers who are working on solving aging. Our April 8th, 2019 episode saw Dr. Mike Lustgarten, Dr. Amy Proal, and Dr. Cosmo Mielke join hosts Dr. Oliver Medvedik…

The March Journal Club hosted by Dr. Oliver Medvedik focused on a recent study that showed transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. These findings support the idea that cognitive decline is in part due to the aging of blood cells,…

On Monday, April 8th, we will be hosting our second Lifespan.io webinar, during which we will be discussing the microbiome and its role in aging and disease. Our second research webinar Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, so to thank them we have launched a new…

For the January Journal Club, we will be taking a look at the recent human senolytics trial conducted at the Mayo Clinic. Abstract Background Cellular senescence is a key mechanism that drives age-related diseases, but has yet to be targeted therapeutically in humans. Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal cellular senescence-associated disease. Selectively…

Our work is largely supported by the generosity of our monthly patrons, the Lifespan Heroes, and this year, we will be showing our appreciation for that support with the launch of a brand new initiative – our new webinar series where you can meet the scientists working on the solutions to aging and age-related diseases….

Tau protein aggregation is associated with cellular senescence in the brain is the topic for the November Journal Club. This is an important paper as it shows how senescent cells contribute to Alzheimer’s disease and how removing them appears to improve the condition. We will see you live on our Facebook page at 13:00 EST for…

We recently did an Ask Me Anything (AMA) event on our Facebook page. We get a lot of questions about our work, many of which are frequent, so we decided that this popular format would be the best way to answer them. The panel featured LEAF Board Directors Keith Comito, Dr. Oliver Medvedik, Elena Milova,…

Earlier this year, we hosted the Ending Age-Related Diseases 2018 conference at the Cooper Union in New York City. This conference was designed to bring together the best in the aging research and biotech investment worlds and saw a range of industry experts sharing their insights. Dr. Oliver Medvedik, LEAF vice president and Director of…

The October Journal Club will be focusing on a new study in worms where a combination of compounds acted in synergy to almost double lifespan. SUMMARY There is growing interest in pharmacological interventions directly targeting the aging process. Pharmacological interventions against aging should be efficacious when started in adults and, ideally, repurpose existing drugs. We…

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