Natural killer (NK) cells are lymphocytes, immune cells which have a powerful arsenal of cytotoxic weaponry that they can use against tumors. Unfortunately, tumors protect themselves using a protective microenvironment that shields them from attack from NK cells. This microenvironment promotes tumor growth and survival and has an immunosuppressive effect that blunts the attempts of…

Today, we are going to have a look at a new study that shows that senescent, non-dividing aged cells can be somewhat restored to working order using a new technique. Before we do that, let’s take a look at what senescent cells are and how cellular senescence protects us from cancer and other harmful diseases….

Atherosclerosis is the number one killer in the world, and science is working on solutions to combat this age-related disease. A new mouse study has shown that the drug trodusquemine can melt away the accumulated arterial plaques that lead to heart attacks and strokes. What is Atherosclerosis? Atherosclerosis is an age-related disease in which toxic,…

As we mentioned in a previous article, the level of interest and support for rejuvenation biotechnology that targets age-related diseases is growing. Over the last few years, we have seen a significant increase in the number of popular science articles, news stories and research papers focusing on the idea that the aging processes are something…

Cytomegalovirus (CMV) is a β-herpesvirus that infects the majority of people in the world, lying dormant and waiting for an opportunity to strike. This persistent virus remains in people for their entire lives once they are infected. CMV contributes to microbial burden as we age, and our dwindling immune cell populations are tied up keeping…

The next Journal Club will be on October 31st at 13:00 EST/18:00 UK and will be streamed live from the Cooper Union, New York, to our Facebook page. The last episode we talked about the hallmarks of aging, a popular aging theory that places the various aging processes into of a number of damage categories (hallmarks) and proposes solutions…

Stem cell aging is a complex topic with many interacting processes and is widely accepted as an important factor in aging. Age-related loss of stem cell function is accompanied by epigenetic changes and alterations to how metabolism functions. Researchers believe that if we can understand the mechanisms underlying these changes, we can likely develop novel…

The levels of circulating inflammatory cytokines and other signaling factors increase with age, contributing to the loss of tissue maintenance, wound healing difficulties, immune system dysfunction, loss of stem cell mobility and a host of other problems. However, it remains a subject of much debate as to what starts the cascade of inflammation that drives…

The use of artificial intelligence and, in particular, machine learning is becoming increasingly popular in research. These systems excel at high-speed data analysis, interpretation, and laborious research tasks, such as image assessment. One of the areas in which machine learning has been enjoying success is image recognition. Now, researchers have begun to use machine learning…

The link between inflammation, cellular senescence, aging, and cancer is a complex relationship, but a new study sheds light on how these four interact. The light and dark side of inflammation and cellular senescence Cellular senescence is a protective mechanism that helps us to stay healthy and avoid cancer by removing damaged and aged cells…

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