Stem cell aging is a complex topic with many interacting processes and is widely accepted as an important factor in aging. Age-related loss of stem cell function is accompanied by epigenetic changes and alterations to how metabolism functions. Researchers believe that if we can understand the mechanisms underlying these changes, we can likely develop novel…

The levels of circulating inflammatory cytokines and other signaling factors increase with age, contributing to the loss of tissue maintenance, wound healing difficulties, immune system dysfunction, loss of stem cell mobility and a host of other problems. However, it remains a subject of much debate as to what starts the cascade of inflammation that drives…

The use of artificial intelligence and, in particular, machine learning is becoming increasingly popular in research. These systems excel at high-speed data analysis, interpretation, and laborious research tasks, such as image assessment. One of the areas in which machine learning has been enjoying success is image recognition. Now, researchers have begun to use machine learning…

The link between inflammation, cellular senescence, aging, and cancer is a complex relationship, but a new study sheds light on how these four interact. The light and dark side of inflammation and cellular senescence Cellular senescence is a protective mechanism that helps us to stay healthy and avoid cancer by removing damaged and aged cells…

Jim Mellon and Al Chalabi are back with another successful venture into the world of science investment. Following their acclaimed 2012 book “Cracking the code”, whose spotlight was on the life sciences industry, Juvenescence takes us on a compelling journey through the dawning market of longevity and rejuvenation biotechnology, which the authors predict will be…

Only two years ago, when I launched my advocacy website Rejuvenaction, I didn’t think I would read a book like Juvenescence so soon; yet, the topic of rejuvenation biotechnologies has already become mainstream enough to lead investors of the calibre of Jim Mellon and Al Chalabi to devote a whole book to it. As Juvenescence…

The immune system is like an army keeping us safe from invasion, injury and infection and helps us to regenerate and repair tissues and organs. However, the immune system is sometimes a double-edged sword that does more harm than good. A lot of focus has been on the role of macrophages and their ability to…

One of the most intriguing questions in biology discusses why some animals can regenerate their major body parts, such as hearts and limbs, and others cannot. A new study led by Dr. James Godwin from the MDI Biological Laboratory suggests that the innate immune system could be the answer. Secrets revealed in salamander study A…

We have talked about the use of artificial intelligence (AI) assessing beauty in an earlier article here. In this video, Anastasia Georgievskaya the project leader for MouseAge talks about how science might overcome some of the issues and shortfalls of past attempts to measure beauty and how it relates to aging research. Anastasia and her team…

The cost of drug discovery and subsequent development is a massive challenge in the pharmaceutical industry. A typical drug can cost upwards of $2.5 billion and a decade or more to identify and test a new drug candidate[1]. In this article, we will be taking a look at the spiraling costs of drug development and…

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