The October Journal Club will be focusing on a new study in worms where a combination of compounds acted in synergy to almost double lifespan. SUMMARY There is growing interest in pharmacological interventions directly targeting the aging process. Pharmacological interventions against aging should be efficacious when started in adults and, ideally, repurpose existing drugs. We…

Senolytics are the first therapies that directly target an aging process in order to delay or prevent age-related diseases, and they are now in human trials. Today, we think that it is the ideal time to have a look at how they work and what companies are involved. Senescent cells and aging As we get…

Today, we want to bring your attention to a recent mouse study on fisetin, a commonly available supplement that has proven effective at destroying senescent cells. What are senescent cells? As we age, increasing amounts of our cells enter into a state known as senescence. Normally, these cells destroy themselves by a self-destruct process known…

Today, we have an update from the MMTP Project team. The project was launched on Lifespan.io back in 2016 with the aim of testing senolytics and their effect on lifespan, it was successfully funded and raised 15% over its initial goal. Hi everyone, it has been a long time so we thought it was time…

Today, we would like to share a talk given by Stephen Hilbert, President of Oisin Biotechnologies, in which he discusses treating aging and cancer by removing harmful senescent cells. On July 12th, we hosted our first conference, Ending Age-Related Diseases: Investment Prospects & Advances in Research, at the Frederick P. Rose Auditorium, which is part…

Today, we want to point out a new publication that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist the programmed cell death known as apoptosis. These cells linger in the body, and, as we age, more and more of them accumulate and contribute…

Citi has produced another of its Disruptive Innovations publications, which takes a look at what it considers to be the top ten disruptive technologies. It is a sign of the changing times that anti-aging medicines are number 2 in its list. 1. All-Solid-State Batteries 2. Anti-Aging Medicines 3. Autonomous Vehicle Networks 4. Big Data &…

Today, we wanted to draw your attention to a recent study showing an association between the accumulation of Tau proteins, which are misfolded proteins that typically indicate Alzheimer’s disease and senescent cells. The researchers also showed that Tau pathology was improved by the use of drugs that remove non-dividing senescent cells. Unfortunately, this journal paper…

Today, we would like to share with you the talk given by Kelsey Moody, CEO of Biotech Company Ichor, at the recent Ending Age-Related Diseases: Investment Prospects & Advances in Research conference in New York City. In this talk, Kelsey discusses Ichor’s protein engineering platform, how Ichor has used it, and Ichor’s plans for using it to…

We interviewed Dr. Peter de Keizer, a researcher who is engaged in studying senescent cells and designing therapies to destroy them in order to delay and prevent age-related diseases. Cleara Biotech is currently using his research to develop a senolytic peptide that accomplishes this via interfering with the interactions between p53 and FOXO4. Senescent cells…

© 2018 - LIFE EXTENSION ADVOCACY FOUNDATION
Privacy Policy / Terms Of Use

       Powered by MMD