Today, we have an interview with Dr. Nichola Conlon, one of the speakers at the Undoing Aging 2018 Conference in Berlin, hosted by the Forever Healthy Foundation and SENS Research Foundation. Introducing Nuchido Dr. Conlon is the CEO of Nuchido, a new company that is set to launch later this year and was encouraged in…

Today, we have a new study showing that a common, plant-based compound could help clear out unwanted senescent cells, which accumulate with age and produce inflammatory signals that drive age-related disease progression. Taking out the trash A new study has investigated a natural, plant-based compound for its ability to destroy senescent cells [1]. These cells…

Today, we have a guest article from Dr. Marion Tible, a scientist, and author over at the aging research-focused blog Long Long Life. What follows is an introduction to the senescent cell-clearing therapies known as senolytics, these therapies are poised to enter human trials and if successful could revolutionize how we treat age-related diseases. What…

Today, we wanted to bring your attention to a new open access paper. The authors here review the role of cellular senescence in the context of the cardiovascular and metabolic diseases of aging. This paper puts special focus on the aging of the vascular system and the role that accumulating numbers of senescent cells play…

Some cancer cells express some of the same genes that senescent cells do, so it makes sense that drugs that destroy senescent cells may also destroy cancer cells. This was what the researchers in this new study set out to test. Abstract p16Ink4a is a potent cell cycle inhibitor engaged to support cell cycle arrest…

The link between inflammation, cellular senescence, aging, and cancer is a complex relationship, but a new study sheds light on how these four interact. The light and dark side of inflammation and cellular senescence Cellular senescence is a protective mechanism that helps us to stay healthy and avoid cancer by removing damaged and aged cells…

So far, the only intervention that is known to consistently increase lifespan across multiple species is caloric restriction (CR). Caloric restriction is known to increase lifespan in the majority of mouse strains tested[1] and many other species. The effects of CR have even been shown to influence how primates age and reduce the incidence of…

There are a number of FDA-approved drugs that have shown efficacy in preclinical studies for addressing the aging process. Drugs such as rapamycin, dasatinib, and quercetin among others have all showed promise in animal studies.  Non-profit Betterhumans, known for its educational and news-related work in the transhumanist community, has announced that it will be running…

By treating one of the root causes of aging – senescent cells – a new class of drugs, known as senolytics, has the potential to treat a wide range of age-related diseases rather than the traditional approach of dealing with them one at a time.  Today we are going to take a look at what…

Researchers at the Mayo Clinic have revealed a causal link between senescent cells and bone loss in mice. Senescent cells are one of the hallmarks of aging, and removing them has been proposed as a way to prevent or delay age-related diseases. As your body ages, increasing amounts of your cells become senescent. Senescent cells…

© 2018 - LIFE EXTENSION ADVOCACY FOUNDATION
Privacy Policy / Terms Of Use

       Powered by MMD