As your body ages, increasing amounts of your cells enter a state of cellular senescence. These cells no longer divide or support the tissues of which they are a part, and they emit a cocktail of harmful chemical signals that encourage other nearby cells to also enter the same senescent state. The presence of senescent…

Cellular senescence is widely considered by academia to be one of the causes of aging and one that leads to a number of age-related diseases. There has been a high level of interest in recent years in cellular senescence and approaches that seek to remove senescent cells as a route to delaying or even preventing…

Oisin Biotechnologies is a rejuvenation biotechnology company which received its seed funding from the Methuselah Foundation and SENS Research Foundation a few years ago. The current focus of Oisin is the targeted clearance of senescent cells, using drugs sometimes referred to as senolytics. Senescent cells are one of the hallmarks of aging, and as they…

The new research work on senolyic drugs by Baar et al. uses a rationally designed molecule that selectively targets senescent cells in vivo, both in an accelerated aging mouse model, and in normally aged mice as well, with few if any side effects[1]. Senolytics are a new class of potential anti-aging drugs that function by specifically…

The breaking news today is that yet another research group has entered the field of senescent cell clearance to treat aging. Therapies that remove senescent cells are known as senolytics and they have been a hot topic for the past year or so. Before we talk about the new study, let’s take a look at…

As your body ages, increasing amounts of your cells enter into a state of senescence. Senescent cells do not divide or support the tissue they are a part of but instead emit a range of potentially harmful chemical signals, which encourage other nearby cells to also enter the same senescent state. Their presence causes many problems:…

CellAge, together with a leading synthetic biology partner, Synpromics, are poised to develop a technology allowing for the identification and removal of harmful senescent cells. Senescent cells accumulate with age until they reach pathological levels and contribute to age-related diseases and chronic inflammation by secreting harmful signals that also poison neighboring cells. This downward spiral…

Our society has never aged more rapidly; one of the most visible symptoms of our changing demographics is an exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly, it causes a significant financial strain…

Announcing A New Goal Structure Hi, everyone! So far, we have raised almost $22,000, which is an amazing effort from the community, and as many people are asking for a more detailed budget, we are going to provide more information and accordingly revise the goal structure of the campaign a bit. A total of $45,000 is enough…

Take a look at our research summary, and watch a mini-interview with Dr. João Pedro de Magalhães about the importance of animal data Hey everyone! The campaign has raised over $9500 so far, which is great and thanks to your support! You are helping to fast-track this research and make a difference. We are happy about two contributions…

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