A particularly harmful byproduct of oxidized cholesterol appears to be a primary cause of atherosclerosis and a therapeutic target ripe for the taking. A new review takes a look at 7-ketocholesterol and its role in aging and disease. A new review exploring 7-ketocholesterol We recently reported on the launch of Underdog Pharma, a new startup…

Today, Underdog Pharma, a spin-off company of SENS Research Foundation, was officially launched with the lofty goal of eradicating atherosclerosis. Atherosclerosis is the leading cause of death worldwide and currently has no effective solution. Current medicine has three broad approaches towards it: lifestyle changes, such as diet and exercise; drugs that reduce the accumulation of…

The MitoMouse campaign has ended, and what a final few days it has been! Thanks to the efforts of the community, an amazing total of $77,525 has been raised in support of this mitochondrial repair project of the SENS Research Foundation. There were 319 people who backed the project and helped to make this the…

Wonderful news today: the MitoMouse project has reached its first stretch goal, and the research will now have even more scope thanks to the efforts of the community. We would like to thank Anthony Jennings, Jose Almeida, Daria Khaltourina, Max Twemlow, Denis Dmitriev, Daniel Smith, and Ingrid Wolf for helping us to hit the first stretch…

Good news for the MitoMouse project! Thanks to the support of the community, LongeCity has already agreed to donate several thousand dollars to the MitoMouse campaign. It plans to expand this support, fully funding the stretch goal of $75,000 if we are able to reach the first $65,000 goal. With just $1460 left to go…

On Friday, October 25, we hosted a Q&A webinar with the team behind MitoMouse, the second MitoSENS program that we are funding. In this webinar, Drs. Aubrey de Grey, Amutha Boominathan, and Matthew “Oki” O’Connor answered viewer questions about the nature of their research and the SENS approach to age-related disease. There are only a…

Wonderful news: the MitoMouse project has successfully reached its initial $50k goal and is well on the way towards the first stretch goal! This means that the project will launch at the lab and the MitoMouse strain will be created. The next step for this ambitious project is to actually create progeny from the SickMice and…

Come and join Dr. Aubrey de Grey, Dr. Amutha Boominathan, Dr. Matthew O’Connor, and others from the SENS Research Foundation team as they answer your questions about aging research on Friday, October 25th. Time: 9 am PDT / 12 pm EDT / 5 pm UK On the day of the event simply join the SENS AMA…

Back in January, we were joined by Dr. Aubrey de Grey, Dr. Amutha Boominathan, Dr. Matthew O’Conner, and Michael Rae from the SENS Research Foundation for a webinar discussion panel focused on MitoSENS, the mitochondrial repair program. During the webinar, a number of points were discussed, and the Lifespan Heroes in the audience got to…

We recently had the opportunity to interview Dr. Amutha Boominathan from the SENS Research Foundation, at the Ending Age-Related Diseases 2019 conference about her research on mitochondrial repair therapies, the value of animal models, and her views on the future of aging research. Dr. Amutha Boominathan received both her MSc and her PhD in Biochemistry from…

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