The March Journal Club hosted by Dr. Oliver Medvedik focused on a recent study that showed transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. These findings support the idea that cognitive decline is in part due to the aging of blood cells,…

Researchers from the University of Luxembourg and the German Cancer Research Center have rejuvenated stem cells in the brains of old mice. The rejuvenated stem cells appear to improve regeneration in areas of damaged or diseased brain tissue. A new way to model stem cells A new study that was published in the journal Cell…

In a world first, a patient with Parkinson’s disease has undergone transplant therapy, which uses reprogrammed stem cells to replace neurons destroyed by the disease. Stem cell therapy is part of the toolkit The stem cell field is an area of science that is relatively well funded and, out of all the branches of medical…

Today, as part of our series on the Hallmarks of Aging, we will be looking at the antagonistic hallmark of stem cell exhaustion. What are stem cells? As explained by an earlier article in this series, while every cell in your body has the same genetic code, regions of DNA are turned off and on…

Today, we are going to take a look at a new study in which scientists at the Walter and Eliza Hall Institute of Medical Research have recently identified a type of cell that appears to be implied in thymic involution—the shrinking of the thymus[1]. Thymic involution is somewhat of a mystery in biology, a phenomenon…

Mesenchymal stem cells (MSCs) are one of the most thoroughly studied and understood stem cell types. They are used in a wide range of therapies, and the many studies using MSCs have enjoyed varied levels of success, depending on delivery methods, patients, co-therapies and other factors. Today, we will be taking a look at MSCs…

Today, we take a look at three key emerging technologies that might add extra healthy years to your life by addressing the aging processes directly to prevent or delay age-related diseases. Senolytics – Removing aged dysfunctional cells to promote tissue regeneration As we age, increasing amounts of our cells enter into a state known as…

We have been talking about a number of new studies in past Journal Clubs, so we thought it was time to get into some aging theory. We chose to cover one of the most cited and highly regarded damage theories of aging in this edition of the club. In this edition of Journal Club, we…

The next Journal Club will be on October 31st at 13:00 EST/18:00 UK and will be streamed live from the Cooper Union, New York, to our Facebook page. The last episode we talked about the hallmarks of aging, a popular aging theory that places the various aging processes into of a number of damage categories (hallmarks) and proposes solutions…

Stem cell aging is a complex topic with many interacting processes and is widely accepted as an important factor in aging. Age-related loss of stem cell function is accompanied by epigenetic changes and alterations to how metabolism functions. Researchers believe that if we can understand the mechanisms underlying these changes, we can likely develop novel…

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