You know the story, and it happens to us all eventually: the older we get, the harder our brains find it to learn and remember new things. There are likely to be a myriad of reasons why the brain gets increasingly worse as we age, but these reasons are still poorly understood. Like the old…

On this talk episode of X10, Nazli Eskici of the University of Helsinki discusses stem cells, the cells that form all the functional cells of the body – and the exhaustion of which is one of the hallmarks of aging. 

A new study recently accepted by iScience has shown that a specific genetic alteration can selectively remove pluripotent stem cells from stem cell therapies in order to purify them for use in treatment. The cells we don’t want As we age, our stem cells both decrease in number and become less efficient in replenishing somatic…

A recent review shows the current state of the industry with regards to using human pluripotent stem cells (hPSCs) to create cells that are useful for the study of, and therapies for, the human heart. Pluripotent Stem Cells Stem cells are the cells that form every other cell in the body, and adult humans naturally…

Aging is a series of processes in which the body’s ability to perform functions gradually decreases. The Hallmarks of Aging includes such things as an increase in senescent cells and a decrease in stem cells, but decreasing NAD+ and increasing free radicals matter as well. This article will cover a few root causes of aging…

Stem cell transplants have been of great interest to aging researchers, and, in a new study, they have successfully increased mouse lifespan by using stem cell therapy. While this has been previously achieved, this experiment was more refined than older studies and sheds new light on the potential of tissue regeneration through stem cells. The…

The March Journal Club hosted by Dr. Oliver Medvedik focused on a recent study that showed transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. These findings support the idea that cognitive decline is in part due to the aging of blood cells,…

Researchers from the University of Luxembourg and the German Cancer Research Center have rejuvenated stem cells in the brains of old mice. The rejuvenated stem cells appear to improve regeneration in areas of damaged or diseased brain tissue. A new way to model stem cells A new study that was published in the journal Cell…

In a world first, a patient with Parkinson’s disease has undergone transplant therapy, which uses reprogrammed stem cells to replace neurons destroyed by the disease. Stem cell therapy is part of the toolkit The stem cell field is an area of science that is relatively well funded and, out of all the branches of medical…

Today, as part of our series on the Hallmarks of Aging, we will be looking at the antagonistic hallmark of stem cell exhaustion. What are stem cells? As explained by an earlier article in this series, while every cell in your body has the same genetic code, regions of DNA are turned off and on…

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