A number of therapies that directly target the aging processes are currently in human trials and could change medicine significantly in the next decade if the results are positive. What is aging? Aging is basically the accumulation of damage and errors caused by a collection of varied processes that harm the functions of the body…

Today, we want to highlight results from human trials in which stem cell transplants have been shown to reduce age-related frailty. Age-related frailty and stem cell transplants Currently, there are no specific approved therapies to address age-related frailty, which can cause elderly people to suffer potentially fatal falls and injuries. There has been considerable interest…

In a world first, a patient with Parkinson’s disease has undergone transplant therapy, which uses reprogrammed stem cells to replace neurons destroyed by the disease. Stem cell therapy is part of the toolkit The stem cell field is an area of science that is relatively well funded and, out of all the branches of medical…

Thanks to a new technique, researchers from the Salk Institute’s Gage laboratory have shown that impaired energy production might be a reason why human brains are susceptible to age-related diseases in the first place [1]. In particular, Salk scientists observed that induced neurons (iNs) obtained from fibroblasts of older individuals had dysfunctional mitochondria and therefore…

Stem cells supply the specialized cells that make up our tissues and organs; every time existing cells are lost for whatever reason, stem cells that can differentiate into that particular type of cell jump into action to compensate for the loss. However, this ability declines over time as aging progresses; indeed, stem cell exhaustion is…

A new open access paper takes a look at the potential of regenerative medicine for the treatment of Alzheimer’s disease [1]. The review covers approaches such as spurring the production of new neurons and transplanting new neurons while taking a look at the disease-modeling approaches and techniques that science is now using to refine approaches…

Korean and Singaporean scientists have recently proposed a new probe to detect cancer stem cells, and it might be an effective seek-and-destroy weapon against a variety of cancer types. In a paper published in the journal Angewandte Chemie earlier this month, the researchers describe a fluorescent dye that they created to highlight cancer stem cells,…

Researchers at the USC Roski Eye Institute, in collaboration with other institutions in California, have shown that a new stem cell-based retinal implant could help people with dry age-related macular degeneration. The researchers have published the results of their phase 1/2a study in the journal Science Translational Medicine [1]. What is dry age-related macular degeneration?…

Researchers at the School of Molecular Sciences at Arizona State University have discovered a potential way to supercharge our stem cells and reverse some aspects of cellular aging. The Hayflick limit Normal cells cannot divide indefinitely; they have a built-in replicative limit, which is often called the Hayflick limit after its discoverer, Leonard Hayflick. This…

Today, we wanted to highlight more progress in a rapidly advancing area of medicine and talk about a new study that uses an exosomes-based approach for stroke treatment that repairs brain tissue. A stem cell-based approach to treating stroke Professor Steven Stice from the University of Georgia (UGA) and Nasrul Hoda of Augusta University led…

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